Size:100ul
$325.00
Discontinued
SKU
OASE00432
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Conjugation Options

OASE00432-FITC Conjugated

OASE00432-HRP Conjugated

OASE00432-Biotin Conjugated

Aha1p Antibody (OASE00432)

Catalog#: OASE00432
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More Information
Predicted Species Reactivity Yeast
Clonality Polyclonal
Host Rabbit
Application WB
Additional Information Background Info: Detects ~ 38kDa. Can run up to 45kDa on SDS Page.
:: Scientific Background: Aha1 is a member of the Hsp90 cochaperone family, and is thought to stimulate Hsp90 ATPase activity by competing with p23 and other co-chaperones for Hsp90 binding (1, 2). It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also interacts with HSPCA/Hsp90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G) (3). Aha1 is expressed in numerous tissues, including the brain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potential therapeutic strategy to increase sensitivity to HSP inhibitors (4).
:: Certificate of Analysis: 0.5 ug/mL was sufficient for detection of Aha1p in 20 ug of W303 yeast lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP asthe secondary antibody.
Reconstitution and Storage Store at -20C. Shipping in Blue Ice or 4C.
Immunogen Yeast Aha1 raised against peptide (CESQVKSNYTRGNQK)-
KLH fusion.
Purification Rabbit antiserum
Datasheets/Manuals Printable datasheet for OASE00432
Dilution 1:2500 (WB)
Target Reference 1. Hainzl O., Lapina M.C., Buchner J., Richter K. (2009) J Biol Chem. Epub.
2. Harst A., Lin H., Obermann W.M. (2005) Biochem J. 387 (pt.3): 789-796.
3. Lotz G.P., Brychzy A., Heinz S., Obermann W.M. (2008) J Cell Sci. 121(pt.5): 717-723.
4. Holmes J.L., Sharp S.Y., Hobbs S., Workman P. (2008) Cancer Res. 68(4): 1188-1197.
Storage Buffer Rabbit antiserum in PBS and 50% glycerol
Gene Symbol AHA1
NCBI Gene Id 851800
Swissprot Id Q12449
Protein Accession # NP_010500.3
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express AHA1.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express AHA1.
  1. What is the species homology for "Aha1p Antibody (OASE00432)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Yeast".

  2. How long will it take to receive "Aha1p Antibody (OASE00432)"?

    This item is available "Domestic: within 3-5 days delivery | International: 3-5 days".

  3. What buffer format is "Aha1p Antibody (OASE00432)" provided in?

    This item is provided in "".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "Aha1p Antibody (OASE00432)"?

    This target may also be called "" in publications.

  5. What is the shipping cost for "Aha1p Antibody (OASE00432)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "Aha1p Antibody (OASE00432)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "Aha1p Antibody (OASE00432)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "Aha1p Antibody (OASE00432)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "AHA1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "AHA1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "AHA1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "AHA1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "AHA1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "AHA1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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