Catalog No: ARP43614_P050
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ARP43614_P050
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Datasheets/ManualsPrintable datasheet for anti-AGT (ARP43614_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Dog, Horse, Rabbit, Sheep
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human AGT
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceDog: 92%; Horse: 85%; Human: 100%; Mouse: 86%; Rabbit: 92%; Rat: 93%; Sheep: 77%
Peptide SequenceSynthetic peptide located within the following region: IHPFHLVIHNESTCEQLAKANAGKPKDPTFIPAPIQAKTSPVDEKALQDQ
Concentration0.5 mg/ml
Blocking PeptideFor anti-AGT (ARP43614_P050) antibody is Catalog # AAP43614 (Previous Catalog # AAPS15808)
Sample Type Confirmation

AGT is supported by BioGPS gene expression data to be expressed in HepG2

ReferenceRavn,L.S., (2008) Pharmacogenet. Genomics 18 (6), 525-533
Gene SymbolAGT
Gene Full NameAngiotensinogen (serpin peptidase inhibitor, clade A, member 8)
Alias SymbolsANHU, hFLT1, SERPINA8
NCBI Gene Id183
Protein NameAngiotensinogen
Description of TargetAGT, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Uniprot IDP01019
Protein Accession #NP_000020
Nucleotide Accession #NM_000029
Protein Size (# AA)485
Molecular Weight53kDa
Protein InteractionsATP6AP2; REN; ACE; ACE2; MME; ECE1; GSDMB; ITSN2; TP53; GRB2; PRG2; ENPEP; PRCP; PREP; MEP1A; AGTR2; KNG1; MAS1; EWSR1; CMA1; CTSG; AGTR1; AGT; DNPEP;
  1. What is the species homology for "AGT Antibody - N-terminal region (ARP43614_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Dog, Horse, Rabbit, Sheep".

  2. How long will it take to receive "AGT Antibody - N-terminal region (ARP43614_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "AGT Antibody - N-terminal region (ARP43614_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "AGT Antibody - N-terminal region (ARP43614_P050)"?

    This target may also be called "ANHU, hFLT1, SERPINA8" in publications.

  5. What is the shipping cost for "AGT Antibody - N-terminal region (ARP43614_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "AGT Antibody - N-terminal region (ARP43614_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "AGT Antibody - N-terminal region (ARP43614_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "53kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "AGT Antibody - N-terminal region (ARP43614_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "AGT"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "AGT"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "AGT"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "AGT"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "AGT"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "AGT"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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