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Catalog No: OPCD01198
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OPCD01198
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Datasheets/ManualsPrintable datasheet for AGRP Recombinant Protein (OPCD01198)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Gly20-Ser130
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceE.coli
TagN-terminal His Tag
Gene SymbolAGRP
Gene Full Nameagouti related neuropeptide
Alias Symbolsagouti related protein homolog;agouti-related protein;AGRT;ART;ASIP2.
NCBI Gene Id181
Protein NameAgouti-related protein
Description of TargetPlays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin system. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R (By similarity). Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner.
Uniprot IDO00253
Protein Accession #NP_001129.1
Nucleotide Accession #NM_001138.1
Protein Size (# AA)Gly20~Ser130
Molecular Weight15kDa
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