Size:100 ug
$315.00
In Stock
SKU
OACA02418
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More Information
Predicted Species Reactivity Human
Product Format Liquid
Clonality Polyclonal
Isotype IgG
Host Rabbit
Application WB, IHC, CHIP
Reconstitution and Storage Store at 4C for up to one month. For long term storage, aliquot and store at -20C or -80C. Avoid freeze thaw cycles.
Immunogen Recombinant human Protein argonaute-2 protein(517-818aa)
Purification Caprylic Acid Ammonium Sulfate Precipitation purified
Predicted Homology Based on Immunogen Sequence Human, Mouse
Datasheets/Manuals Printable datasheet for anti-AGO2 (OACA02418) antibody
Specificity Human
Formulation Provided in PBS, pH 7.4, 50% Glycerol, 0.03% Proclin 300
Target Reference [1] The crystal structure of human Argonaute2. Schirle N.T., MacRae I.J. Science 336:1037-1040 (2012).
[2] The structure of human argonaute-2 in complex with miR-20a. Elkayam E., Kuhn C.D., Tocilj A., Haase A.D., Greene E.M., Hannon G.J., Joshua-Tor L. Cell 150:100-110 (2012).
[3] Structural analysis of 5\'-mRNA-cap interactions with the human AGO2 MID domain. Frank F., Fabian M.R., Stepinski J., Jemielity J., Darzynkiewicz E., Sonenberg N., Nagar B. EMBO Rep. 12:415-420 (2011).
Gene Symbol AGO2
Official Gene Full Name argonaute 2, RISC catalytic component
Alias Symbols Q10, EIF2C2
NCBI Gene Id 27161
Protein Name protein argonaute-2
Description of Target This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing. Multiple transcript variants encoding different isoforms have been found for this gene.
Swissprot Id Q9UKV8
Protein Accession # NP_001158095.1
Nucleotide Accession # NM_001164623.1
Protein Size (# AA) 859
Molecular Weight 97 kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express AGO2.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express AGO2.
  1. What is the species homology for "AGO2 Antibody (OACA02418)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "AGO2 Antibody (OACA02418)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".

  3. What buffer format is "AGO2 Antibody (OACA02418)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "AGO2 Antibody (OACA02418)"?

    This target may also be called "Q10, EIF2C2" in publications.

  5. What is the shipping cost for "AGO2 Antibody (OACA02418)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "AGO2 Antibody (OACA02418)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "AGO2 Antibody (OACA02418)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "97 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "AGO2 Antibody (OACA02418)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "AGO2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "AGO2"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "AGO2"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "AGO2"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "AGO2"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "AGO2"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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