Search Antibody, Protein, and ELISA Kit Solutions

AGO2 Antibody (OACA02418)

100 ug
$315.00
In Stock
Request Bulk Order Quote

Predicted Species Reactivity:
Human
Product Format:
Liquid
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Application:
WB, IHC, CHIP
Reconstitution and Storage:
Store at 4C for up to one month. For long term storage, aliquot and store at -20C or -80C. Avoid freeze thaw cycles.
Immunogen:
Recombinant human Protein argonaute-2 protein(517-818aa)
Purification:
Caprylic Acid Ammonium Sulfate Precipitation purified
Predicted Homology Based on Immunogen Sequence:
Human, Mouse
Datasheets/Manuals:
Printable datasheet for anti-AGO2 (OACA02418) antibody
Specificity:
Human
Formulation:
Provided in PBS, pH 7.4, 50% Glycerol, 0.03% Proclin 300
Target Reference:
[1] The crystal structure of human Argonaute2. Schirle N.T., MacRae I.J. Science 336:1037-1040 (2012).
[2] The structure of human argonaute-2 in complex with miR-20a. Elkayam E., Kuhn C.D., Tocilj A., Haase A.D., Greene E.M., Hannon G.J., Joshua-Tor L. Cell 150:100-110 (2012).
[3] Structural analysis of 5\'-mRNA-cap interactions with the human AGO2 MID domain. Frank F., Fabian M.R., Stepinski J., Jemielity J., Darzynkiewicz E., Sonenberg N., Nagar B. EMBO Rep. 12:415-420 (2011).
Gene Symbol:
AGO2
Official Gene Full Name:
argonaute 2, RISC catalytic component
Alias Symbols:
Q10, EIF2C2
NCBI Gene Id:
27161
Protein Name:
protein argonaute-2
Description of Target:
This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing. Multiple transcript variants encoding different isoforms have been found for this gene.
Swissprot Id:
Q9UKV8
Protein Accession #:
NP_001158095.1
Nucleotide Accession #:
NM_001164623.1
Protein Size (# AA):
859
Molecular Weight:
97 kDa
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express AGO2.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express AGO2.

Product Reviews

Protocol:
Tips Information:

Tell us what you think about this item!

Write A Review
    Please, wait...