AFM Antibody - middle region (ARP33804_P050)

Size:100 ul

Human HepG2

Human Placenta, Human Liver

Basic Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Guinea Pig, Human
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Replacement Item: This antibody may replace item sc-74313 from Santa Cruz Biotechnology.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human AFM
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Guinea Pig: 79%; Human: 100%
• Complete computational species homology data: Anti-AFM (ARP33804_P050)
• Peptide Sequence: Synthetic peptide located within the following region: GQCIINSNKDDRPKDLSLREGKFTDSENVCQERDADPDTFFAKFTFEYSR
• Concentration: Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
• Blocking Peptide: For anti-AFM (ARP33804_P050) antibody is Catalog # AAP33804 (Previous Catalog # AAPP04870)
• Datasheets/Manuals: Printable datasheet for anti-AFM (ARP33804_P050) antibody
• Target Reference: Jerkovic,L., et al., (2005) J. Proteome Res. 4 (3), 889-899
• Publications:

  Hu, Z. et al. Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity. Theranostics 4, 215-28 (2014). WB, Guinea Pig, Human 24465277

  Penno, M. A. S. et al. 2D-DIGE analysis of sera from transgenic mouse models reveals novel candidate protein biomarkers for human gastric cancer. J. Proteomics 77, 40-58 (2012). WB, Guinea Pig, Human 22789672

Target Info

• Gene Symbol: AFM
• Official Gene Full Name: Afamin
• Alias Symbols: ALF, ALB2, ALBA
• NCBI Gene Id: 173
• Protein Name: Afamin
• Description of Target: AFM is a member of the albumin gene family, which is comprised of four genes that localize to chromosome 4 in a tandem arrangement. These four genes encode structurally-related serum transport proteins that are known to be evolutionarily related. AFM is regulated developmentally, expressed in the liver and secreted into the bloodstream.This gene is a member of the albumin gene family, which is comprised of four genes that localize to chromosome 4 in a tandem arrangement. These four genes encode structurally-related serum transport proteins that are known to be evolutionarily related. The protein encoded by this gene is regulated developmentally, expressed in the liver and secreted into the bloodstream.
• Swissprot Id: P43652
• Protein Accession #: NP_001124
• Nucleotide Accession #: NM_001133
• Protein Size (# AA): 599
• Molecular Weight: 69kDa
• Tissue Tool: Find tissues and cell lines supported by DNA array analysis to express AFM.
• RNA Seq: Find tissues and cell lines supported by RNA-seq analysis to express AFM.