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- $55: Antibody & Protein in US
- $55 + $25/Kit in US
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| Datasheets/Manuals | Printable datasheet for AFG3L2 Antibody - FITC Conjugated (OACA01138) (OACA01138) |
|---|
| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Liquid |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Conjugation | FITC |
| Application | WB |
| Reconstitution and Storage | -20°C or -80°C |
| Immunogen | Recombinant Human AFG3-like protein 2 protein (550-759AA) |
| Purification | Protein G Purified |
| Purity | Caprylic Acid Ammonium Sulfate Precipitation |
| Reference | [1] Identification and characterization of AFG3L2, a novel paraplegin-related gene.'Banfi S., Bassi M.T., Andolfi G., Marchitiello A., Zanotta S., Ballabio A., Casari G., Franco B.Genomics 59:51-58(1999) [2] The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).'The MGC Project TeamGenome Res. 14:2121-2127(2004) [3] Lysine acetylation targets protein complexes and co-regulates major cellular functions.'Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T., Olsen J.V., Mann M.Science 325:834-840(2009) |
| Storage Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Gene Symbol | AFG3L2 |
|---|---|
| Gene Full Name | AFG3 like matrix AAA peptidase subunit 2 |
| Alias Symbols | AFG3 ATPase family gene 3-like 2;AFG3 ATPase family member 3-like 2;AFG3 like AAA ATPase 2;AFG3-like protein 2;ATPase family gene 3, yeast;OPA12;paraplegin-like protein;SCA28;SPAX5. |
| NCBI Gene Id | 10939 |
| Protein Name | AFG3-like protein 2 |
| Description of Target | ATP-dependent protease which is essential for axonal and neuron development. In neurons, mediates degradation of SMDT1/EMRE before its assembly with the uniporter complex, limiting the availability of SMDT1/EMRE for MCU assembly and promoting efficient assembly of gatekeeper subunits with MCU (PubMed:27642048). Required for the maturation of paraplegin (SPG7) after its cleavage by mitochondrial-processing peptidase (MPP), converting it into a proteolytically active mature form (By similarity). |
| Uniprot ID | Q9Y4W6 |
| Protein Accession # | NP_006787.2 |
| Nucleotide Accession # | NM_006796.2 |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "AFG3L2 Antibody - FITC Conjugated (OACA01138)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "AFG3L2 Antibody - FITC Conjugated (OACA01138)"?
This item is available "Domestic: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks | International: Antibody & Kits: 2 weeks | Proteins: 4-6 weeks".
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What buffer format is "AFG3L2 Antibody - FITC Conjugated (OACA01138)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "AFG3L2 Antibody - FITC Conjugated (OACA01138)"?
This target may also be called "AFG3 ATPase family gene 3-like 2;AFG3 ATPase family member 3-like 2;AFG3 like AAA ATPase 2;AFG3-like protein 2;ATPase family gene 3, yeast;OPA12;paraplegin-like protein;SCA28;SPAX5." in publications.
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What is the shipping cost for "AFG3L2 Antibody - FITC Conjugated (OACA01138)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "AFG3L2 Antibody - FITC Conjugated (OACA01138)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "AFG3L2 Antibody - FITC Conjugated (OACA01138)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "AFG3L2 Antibody - FITC Conjugated (OACA01138)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "AFG3L2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "AFG3L2"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "AFG3L2"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "AFG3L2"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "AFG3L2"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "AFG3L2"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
