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| Datasheets/Manuals | Printable datasheet for anti-ADRA2C (ARP59968_P050) antibody |
|---|
| Tested Species Reactivity | Human |
|---|---|
| Predicted Species Reactivity | Human, Pig |
| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | WB |
| Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | The immunogen is a synthetic peptide directed towards the C-terminal region of human ADRA2C |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Human: 100%; Pig: 85% |
| Peptide Sequence | Synthetic peptide located within the following region: RAGAEGGAGGADGQGAGPGAAESGALTASREWGGERGRPLCLPPSARGCF |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-ADRA2C (ARP59968_P050) antibody is Catalog # AAP59968 |
| Gene Symbol | ADRA2C |
|---|---|
| Gene Full Name | adrenoceptor alpha 2C |
| Alias Symbols | ADRA2L2, ADRARL2, ADRA2RL2, ALPHA2CAR |
| NCBI Gene Id | 152 |
| Protein Name | alpha-2C adrenergic receptor |
| Description of Target | Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. |
| Uniprot ID | P18825 |
| Protein Accession # | NP_000674.2 |
| Nucleotide Accession # | NM_000683.3 |
| Protein Size (# AA) | 374 |
| Molecular Weight | 41kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "ADRA2C Antibody - C-terminal region (ARP59968_P050)"?
The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Pig".
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How long will it take to receive "ADRA2C Antibody - C-terminal region (ARP59968_P050)"?
This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".
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What buffer format is "ADRA2C Antibody - C-terminal region (ARP59968_P050)" provided in?
This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "ADRA2C Antibody - C-terminal region (ARP59968_P050)"?
This target may also be called "ADRA2L2, ADRARL2, ADRA2RL2, ALPHA2CAR" in publications.
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What is the shipping cost for "ADRA2C Antibody - C-terminal region (ARP59968_P050)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "ADRA2C Antibody - C-terminal region (ARP59968_P050)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "ADRA2C Antibody - C-terminal region (ARP59968_P050)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "41kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "ADRA2C Antibody - C-terminal region (ARP59968_P050)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "ADRA2C"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "ADRA2C"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "ADRA2C"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "ADRA2C"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "ADRA2C"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "ADRA2C"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
