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Catalog No: OPCD01152
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OPCD01152
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Datasheets/ManualsPrintable datasheet for ADRA1A Recombinant Protein (OPCD01152)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Ser330-Val466
::Subcellular Location: Nucleus membrane; Multi-pass membrane protein. Cell membran
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceE.coli
TagN-terminal His Tag
Gene SymbolADRA1A
Gene Full Nameadrenoceptor alpha 1A
Alias SymbolsADRA1C;ADRA1L1;alpha-1A adrenergic receptor;alpha-1A adrenoceptor;alpha-1A adrenoreceptor;ALPHA1AAR;alpha-1C adrenergic receptor;Alpha-adrenergic receptor 1c;G protein coupled receptor.
NCBI Gene Id148
Protein NameAlpha-1A adrenergic receptor
Description of TargetThis alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine(PE)-stimulated ERK signaling in cardiac myocytes.
Uniprot IDP35348
Protein Accession #NP_000671.2
Nucleotide Accession #NM_000680.3
Protein Size (# AA)Ser330~Val466
Molecular Weight22kDa
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