Size:100 ul
Special Price $229.00 Regular Price $319.00
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SKU
ARP59956_P050
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Conjugation Options

ARP59956_P050-FITC Conjugated

ARP59956_P050-HRP Conjugated

ARP59956_P050-Biotin Conjugated

ADORA3 Antibody - C-terminal region (ARP59956_P050)

Catalog#: ARP59956_P050
Domestic: within 1-2 days delivery International: 1-2 days
More Information
Tested Species Reactivity Human
Predicted Species Reactivity Cow, Horse, Human, Pig, Rabbit
Product Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Clonality Polyclonal
Host Rabbit
Application IHC, WB
Reconstitution and Storage For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Replacement Item This antibody may replace item sc-115823 from Santa Cruz Biotechnology.
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human ADORA3
Purification Affinity Purified
Predicted Homology Based on Immunogen Sequence Cow: 75%; Horse: 93%; Human: 100%; Pig: 85%; Rabbit: 77%
Complete computational species homology data Anti-ADORA3 (ARP59956_P050)
Peptide Sequence Synthetic peptide located within the following region: RSCKAPKVVRKADRSRTSILIICILITGLGIISVISHLTKRRRSQRNRRV
Concentration Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Blocking Peptide For anti-ADORA3 (ARP59956_P050) antibody is Catalog # AAP59956 (Previous Catalog # AAPP46118)
Datasheets/Manuals Printable datasheet for anti-ADORA3 (ARP59956_P050) antibody
Publications

Merighi, S. et al. Hypoxia inhibits paclitaxel-induced apoptosis through adenosine-mediated phosphorylation of bad in glioblastoma cells. Mol. Pharmacol. 72, 162-72 (2007). IHC, WB, Cow, Horse, Human, Pig, Rabbit 17400763

Gene Symbol ADORA3
Official Gene Full Name Adenosine A3 receptor
Alias Symbols A3AR, AD026, bA552M11.5, RP11-552M11.7
NCBI Gene Id 140
Protein Name Protein ADORA3, isoform 3
Description of Target This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Multiple transcript variants encoding different isoforms have been found for this gene.
Swissprot Id Q5QNY7
Protein Accession # NP_001075445
Nucleotide Accession # NM_001081976
Protein Size (# AA) 266
Molecular Weight 30kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express ADORA3.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express ADORA3.
Protein Interactions YWHAQ; YWHAZ;
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