ADNP Antibody - N-terminal region (OASG00229)

Catalog No: OASG00229

Size:100 uL

Western Blot using Lovo

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: Liquid PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, IHC
  Cellular Localization: Nucleus
  Tissue Specificity: Widely expressed. Strong expression in heart, skeletal muscle, kidney and placenta. In brain, expression is stronger in the cerebellum and cortex regions. No expression detected in the colon. Strong increase of expression in colon and breast cancer tissues.
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from the N-terminal region of human ADNP. Location: 80-160aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Specificity: ADNP Polyclonal Antibody detects endogenous levels of ADNP protein.
• Application Info: WB: 1:500~2000
  IHC: 1:100~300
  ELISA: 1:5000

Target Info

• Gene Symbol: ADNP
• Gene Full Name: activity-dependent neuroprotector homeobox
• Alias Symbols: ADNP1, HVDAS, MRD28
• NCBI Gene Id: 23394;
• Description of Target: ADNP is a protein encoded by the ADNP gene which is approximately 123,5 kDa. It is a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. It may also increase the viability of certain cell types through modulation of p53 activity. ADNP is widely expressed with strong expression in heart, skeletal muscle, kidney and placenta. Mutations in the ADNP gene may result in Helsmoortel-van der Aa syndrome.
• Uniprot ID: Q9H2P0, Q9Z103
• Molecular Weight: 124 kDa