ADGRB3 Antibody - N-terminal region (OASG00699)

Catalog No: OASG00699 (Formerly GWB-YYLT0A)

Size:100 uL

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: Liquid. PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: IHC, IF
  Function: Receptor that plays a role in the regulation of synaptogenesis and dendritic spine formation at least partly via interaction with ELMO1 and RAC1 activity (By similarity). Promotes myoblast fusion through ELMO/DOCK1.
  Tissue Specificity: Strongly expressed in brain. Also detected in heart. Reduced expression in some glioblastoma cell lines.
  Cellular Localization: Cell membrane / Multi-pass membrane protein.
  Sequence and Domain Family: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. / Contains 1 CUB domain. / Contains 1 GPS domain. / Contains 4 TSP type-1 domains.
  Post-translational Modifications: The endogenous protein is proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit.
  
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from the N-terminal region of human BAI-3. Location: 180-260aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Specificity: BAI-3 Polyclonal Antibody detects endogenous levels of BAI-3 protein.
• Intended Use: For research use only.
• Application Info: IHC 1:100~300
  IF 1:200~1000
  ELISA 1:10000
  

Target Info

• Gene Symbol: ADGRB3
• Gene Full Name: adhesion G protein-coupled receptor B3
• Alias Symbols: BAI3
• NCBI Gene Id: 577; 210933;
• Uniprot ID: O60242, Q80ZF8
• Molecular Weight: 171 kDa