Catalog No: OPCD01129
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OPCD01129
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Datasheets/ManualsPrintable datasheet for ADCYAP1 Recombinant Protein (OPCD01129)
Product Info
Predicted Species ReactivityMouse|Mus musculus
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Met1-Leu175
::Subcellular Location: Secreted
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceE.coli
TagN-terminal His Tag
Gene SymbolAdcyap1
Gene Full Nameadenylate cyclase activating polypeptide 1
Alias SymbolsP;PACAP;pituitary adenylate cyclase-activating polypeptide.
NCBI Gene Id11516
Protein NamePituitary adenylate cyclase-activating polypeptide
Description of TargetBinding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells (By similarity). Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway (By similarity). In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion (By similarity). Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells (PubMed:23913443).
Uniprot IDO70176
Protein Accession #NP_001302432.1
Nucleotide Accession #NM_001315503.1
Protein Size (# AA)Met1~Leu175
Molecular Weight23.07kDa
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