Catalog No: OPCD01128
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OPCD01128
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Datasheets/ManualsPrintable datasheet for ADCYAP1 Recombinant Protein (OPCD01128)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Ile17-Leu176
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceE.coli
TagN-terminal His and GST Tag
Gene SymbolADCYAP1
Gene Full Nameadenylate cyclase activating polypeptide 1
Alias Symbolsadenylate cyclase activating polypeptide 1 (pituitary);PACAP;pituitary adenylate cyclase-activating polypeptide;prepro-PACAP.
NCBI Gene Id116
Protein NamePituitary adenylate cyclase-activating polypeptide
Description of TargetBinding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion (By similarity). Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells (By similarity).
Uniprot IDP18509
Protein Accession #NP_001093203.1
Nucleotide Accession #NM_001099733.1
Protein Size (# AA)Ile17~Leu176
Molecular Weight47kDa
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