ADAMTSL5 Antibody (OAPB01080)

Catalog No: OAPB01080

Size:100UG

Western blot analysis of ADAMTSL5 in human skeletal muscle tissue lysate with ADAMTSL5 antibody at 1 μg/mL.

Immunohistochemistry of ADAMTSL5 in mouse skeletal muscle tissue with ADAMTSL5 antibody at 5 μg/mL.

Immunofluorescence of ADAMTSL5 in mouse skeletal muscle tissue with ADAMTSL5 antibody at 20 μg/mL.

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Liquid. ADAMTSL5 Antibody is supplied in PBS containing 0.02% sodium azide.
• Clonality: Polyclonal
• Host: chicken
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
• Additional Information: Product Description: ADAMTSL5 belongs to a large superfamily containing 20 ADAMTS proteases and at least eight ADAMTS-like proteins. ADAMTS proteases are secreted enzymes with a conserved organization that includes a metalloprotease domain and an ancillary domain containing one or more thrombospondin type 1 repeats (TSR). The ADAMTS-like subfamily comprises proteins homologous to the ADAMTS ancillary domains but lacking the protease domain and hence lacking catalytic activity. The exact role of ADAMTSL5 is currently unknown, but other ADAMTS-like proteins appear to have regulatory roles in the extracellular matrix.
  Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
• Reconstitution and Storage: ADAMTSL5 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Immunogen: ADAMTSL5 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human ADAMTSL5. The immunogen is located within the last 50 amino acids of ADAMTSL5.
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Human; Mouse; Rat
• Concentration: 1 mg/ml
• Blocking Peptide: For anti-ADAMTSL5 (OAPB01080) antibody is Catalog # OEPB03197
• Application Info: ADAMTSL5 antibody can be used for detection of ADAMTSL5 by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)
• Reference: Jones GC and Riley GP. ADAMTS proteinases: a multi-domain, multi-functional family with roles in extracellular matrix turnover and arthritis. Arth. Res. and Ther.2005; 7:160-9.;Apte SS. A disintegrin-like and metalloprotease (reprolysin-type) with thrombospondin type 1 motif (ADAMTS) superfamily: functions and mechanisms. J. Biol. Chem.2009; 284:31493-7.;

Target Info

• Gene Symbol: ADAMTSL5
• Gene Full Name: ADAMTS like 5
• Alias Symbols: ADAMTSL-5;ADAMTS-like protein 5;thrombospondin type-1 domain-containing protein 6;thrombospondin, type I, domain containing 6;THSD6.
• NCBI Gene Id: 339366
• Protein Name: ADAMTS-like protein 5|ADAMTS-like protein 5 isoform 2 precursor [Homo sapiens]
• Description of Target: May play a role in modulation of fibrillin microfibrils in the extracellular matrix (ECM).
• Uniprot ID: Q6ZMM2
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/NP_998769
• Nucleotide Accession #: NM_213604.2; XM_005259549.3