Size:100 ug
$229.00
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SKU
OABB00433
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ADAMTS4 Polyclonal Antibody (OABB00433)

Catalog#: OABB00433
Domestic: within 1 week delivery | International: 1 week
This product is Genway GWB-BBP356
More Information
Predicted Species Reactivity Human, Mouse, Rat
Product Format Lyophilized
Clonality Polyclonal
Application WB
Additional Information Content: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3
:: Background: ADAMTS4, A disintegrin and metalloproteinase with thrombospondin motifs 4 is an enzyme that in humans is encoded by the ADAMTS4 gene. ADAMTS4 is a member of the large ADAMTS family of zinc-dependent proteases. The human ADAMTS4 gene is mapped to chromosome 1 by somatic cell hybrid analysis. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.
Reconstitution and Storage 0.2ml of distilled water will yield a concentration of 500ug/ml. At -20C for one year. After reconstitution, at 4C for one month. It can
also be aliquotted and stored frozen at -20C for a longer time.
Avoid repeated freezing and thawing.
Replacement Item This antibody may replace item sc-16533 from Santa Cruz Biotechnology.
Immunogen A synthetic peptide corresponding to a sequence at the C-terminal ofhuman ADAMTS4, different from the related rat and mouse sequencesby three amino acids.
Purification Immunogen affinity purified.
Predicted Homology Based on Immunogen Sequence Human; Mouse; Rat
Datasheets/Manuals Printable datasheet for OABB00433
Specificity Rabbit IgG
Target Reference 1. Hurskainen, T. L., Hirohata, S., Seldin, M. F., Apte, S. S.ADAM-TS5, ADAM-TS6, and ADAM-TS7,
novel members of a new family of zinc metalloproteases: general features and genomic distribution
of the ADAM-TS family.J. Biol. Chem. 274: 25555-25563, 1999.
2. Tang, B. L., Hong, W.ADAMTS: a novel family of proteases with an ADAM protease domain and
thrombospondin 1 repeats.FEBS Lett. 445: 223-225, 1999.
3. Tortorella, M. D., Burn, T. C., Pratta, M. A., Abbaszade, I., Hollis, J. M., Liu, R., Rosenfeld, S. A.,
Copeland, R. A., Decicco, C. P., Wynn, R., Rockwell, A., Yang, F., and 16 others.Purification and
cloning of aggrecanase-1: a member of the ADAMTS family of proteins.Science 284: 1664-1666,
1999
Gene Symbol Adamts4
NCBI Gene Id 66015
Protein Name A disintegrin and metalloproteinase with thrombospondin motifs 4
Swissprot Id Q9ESP7
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express Adamts4.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express Adamts4.
  1. What is the species homology for "ADAMTS4 Polyclonal Antibody (OABB00433)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".

  2. How long will it take to receive "ADAMTS4 Polyclonal Antibody (OABB00433)"?

    This item is available "Domestic: within 1 week delivery | International: 1 week".

  3. What buffer format is "ADAMTS4 Polyclonal Antibody (OABB00433)" provided in?

    This item is provided in "Lyophilized".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "ADAMTS4 Polyclonal Antibody (OABB00433)"?

    This target may also be called "" in publications.

  5. What is the shipping cost for "ADAMTS4 Polyclonal Antibody (OABB00433)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "ADAMTS4 Polyclonal Antibody (OABB00433)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "ADAMTS4 Polyclonal Antibody (OABB00433)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "ADAMTS4 Polyclonal Antibody (OABB00433)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "ADAMTS4"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ADAMTS4"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ADAMTS4"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ADAMTS4"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ADAMTS4"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ADAMTS4"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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