ADAM9 Antibody - middle region (ARP46373_P050)

Catalog No: ARP46373_P050

WB Suggested Anti-ADAM9 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: 293T cell lysate

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ADAM9
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%
• Peptide Sequence: Synthetic peptide located within the following region: NKGGNCLLNIPKPDEAYSAPSCGNKLVDAGEECDCGTPKECELDPCCEGS
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-ADAM9 (ARP46373_P050) antibody is Catalog # AAP46373 (Previous Catalog # AAPP27158)
• Reference: Zigrino,P., (2007) J. Biol. Chem. 282 (42), 30785-30793

Target Info

• Gene Symbol: ADAM9
• Gene Full Name: ADAM metallopeptidase domain 9
• Alias Symbols: MCMP, MDC9, CORD9, Mltng
• NCBI Gene Id: 8754
• Protein Name: Disintegrin and metalloproteinase domain-containing protein 9
• Description of Target: ADAM9 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM9 interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Two alternative splice variants have been identified, encoding distinct isoforms.
• Uniprot ID: B7ZLN7
• Protein Accession #: NP_001005845
• Nucleotide Accession #: NM_001005845
• Protein Size (# AA): 655
• Molecular Weight: 69kDa
• Protein Interactions: UBC; RNF2; CDH1; SH3D19; SH3GLB1; SNX9; MAD2L2; ITGA3; ITGAV; TNF; PRKCD; ITGA6; SH3GL2;