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ADAM10 Antibody - middle region (OAGA02442)

100 ul
$409.00
In Stock
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Predicted Species Reactivity:
Human
Product Format:
Liquid. 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Clonality:
Polyclonal
Isotype:
IgG
Host:
Rabbit
Application:
IHC-P, WB
Reconstitution and Storage:
Store as a concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze/thaw cycles.
Gene Symbol:
ADAM10
Official Gene Full Name:
ADAM metallopeptidase domain 10
NCBI Gene Id:
102
Swissprot Id:
O14672
Alias Symbols:
RAK, kuz, AD10, AD18, MADM, CD156c, HsT18717
Replacement Item:
This antibody may replace item sc-16523 from Santa Cruz Biotechnology.
Description of Target:
Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin.
Molecular Weight:
84 kDa
Purification:
Purified by antigen-affinity chromatography.
Tissue Tool:
Find tissues and cell lines supported to express ADAM10.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express ADAM10.
Immunogen:
Recombinant protein encompassing a sequence within the center region of human ADAM10. The exact sequence is proprietary.
Predicted Homology Based on Immunogen Sequence:
Mouse (94%), Rat (95%), Xenopus laevis (84%), Pig (98%), Chicken (90%), Bovine (97%)
Concentration:
0.48 mg/ml
Datasheets/Manuals:
Printable datasheet for anti-ADAM10 (OAGA02442) antibody
Application Info:
WB 1:500~3000
IHC-FFPE 1:100~1000
Publications:
Sogorb-Esteve, A., García-Ayllón, M., Gobom,J., Alom, J., Zetterberg, H., Blennow, K. and Sáez-Valero, J. Levels of ADAM10 are reduced in Alzheimer’s disease CSF. J Neuroinflammation. 2018; 15: 213. 30045733

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