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ADAM10 Antibody - middle region (OAGA02442)
| Datasheets/Manuals | Printable datasheet for anti-ADAM10 (OAGA02442) antibody |
|---|
| Predicted Species Reactivity | Human |
|---|---|
| Product Format | Liquid.0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Application | IHC-P, WB |
| Reconstitution and Storage | Store as a concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze/thaw cycles. |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human ADAM10. The exact sequence is proprietary. |
| Purification | Purified by antigen-affinity chromatography. |
| Concentration | Varies by lot. See vial for concentration. |
| Application Info | WB 1:500~3000 IHC-P 1:100~1000 |
| Publications | Sogorb-Esteve, A., GarcÃa-Ayllón, M., Gobom, J., Alom, J., Zetterberg, H., Blennow, K. and Sáez-Valero, J. Levels of ADAM10 are reduced in Alzheimer’s disease CSF. J Neuroinflammation. 15, 213 (2018). 30045733 α-Secretase nonsense mutation (ADAM10 Tyr167*) in familial Alzheimer's disease. Alzheimers Res Ther. 12, 139 (2020). 33129344 |
| Description |
| Gene Symbol | ADAM10 |
|---|---|
| Gene Full Name | ADAM metallopeptidase domain 10 |
| Alias Symbols | RAK, kuz, AD10, AD18, MADM, CD156c, CDw156, HsT18717 |
| NCBI Gene Id | 102 |
| Description of Target | Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. |
| Uniprot ID | O14672 |
| Molecular Weight | 84 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "ADAM10 Antibody - middle region (OAGA02442)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".
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How long will it take to receive "ADAM10 Antibody - middle region (OAGA02442)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
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What buffer format is "ADAM10 Antibody - middle region (OAGA02442)" provided in?
This item is provided in "Liquid.0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "ADAM10 Antibody - middle region (OAGA02442)"?
This target may also be called "RAK, kuz, AD10, AD18, MADM, CD156c, CDw156, HsT18717" in publications.
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What is the shipping cost for "ADAM10 Antibody - middle region (OAGA02442)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "ADAM10 Antibody - middle region (OAGA02442)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "ADAM10 Antibody - middle region (OAGA02442)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "84 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "ADAM10 Antibody - middle region (OAGA02442)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "ADAM10"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "ADAM10"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "ADAM10"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "ADAM10"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "ADAM10"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "ADAM10"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.
