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ADA antibody - N-terminal region (ARP51757_P050)

100 ul
$289.00
In Stock
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Conjugation Options

ARP51757_P050-FITC Conjugated

ARP51757_P050-HRP Conjugated

ARP51757_P050-Biotin Conjugated

Gene Symbol:
ADA
NCBI Gene Id:
100
Official Gene Full Name:
Adenosine deaminase
Protein Name:
Adenosine deaminase
Swissprot Id:
P00813
Protein Accession #:
NP_000013
Nucleotide Accession #:
NM_000022
Alias Symbols:
-
Replacement Item:
This antibody may replace item sc-158238 from Santa Cruz Biotechnology.
Description of Target:
ADA is an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this gene and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia.
Protein Size (# AA):
363
Molecular Weight:
41kDa
Host:
Rabbit
Clonality:
Polyclonal
Purification:
Affinity Purified
Application:
WB
Tissue Tool:
Find tissues and cell lines supported by DNA array analysis to express ADA.
RNA Seq:
Find tissues and cell lines supported by RNA-seq analysis to express ADA.
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human ADA
Tested Species Reactivity:
Human
Predicted Homology Based on Immunogen Sequence:
Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Complete computational species homology data:
Anti-ADA (ARP51757_P050)
Peptide Sequence:
Synthetic peptide located within the following region: AIAGCREAIKRIAYEFVEMKAKEGVVYVEVRYSPHLLANSKVEPIPWNQA
Product Format:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and Storage:
For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Concentration:
Batch dependent within range: 100 ul at 0.5 - 1 mg/ml
Protein Interactions:
UBC; SGCD; PIAS2; TERF2IP; TINF2; ADORA2B; DPP4; NR3C1; DRD1; GRB2; ADORA2A; ADORA1;
Blocking Peptide:
For anti-ADA (ARP51757_P050) antibody is Catalog # AAP51757 (Previous Catalog # AAPP40132)
Datasheets/Manuals:
Printable datasheet for anti-ADA (ARP51757_P050) antibody
Publications:

Ferrante, A. et al. Expression, pharmacology and functional activity of adenosine A1 receptors in genetic models of Huntington’s disease. Neurobiol. Dis. 71C, 193-204 (2014). WB, Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat 25132555

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