Catalog No: ARP52836_P050
Price: $0.00
SKU
ARP52836_P050
Availability: Domestic: within 1-2 days delivery | International: 1-2 days
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  • $55: Antibody & Protein in US
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Datasheets/ManualsPrintable datasheet for anti-ACVR1C (ARP52836_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human ACVR1C
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 83%; Guinea Pig: 80%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 81%; Rabbit: 100%; Rat: 86%
Peptide SequenceSynthetic peptide located within the following region: QVFCHSSNNVTKTECCFTDFCNNITLHLPTASPNAPKLGPMELAIIITVP
Concentration0.5 mg/ml
Blocking PeptideFor anti-ACVR1C (ARP52836_P050) antibody is Catalog # AAP52836 (Previous Catalog # AAPP33844)
ReferenceAndersson,O., (2008) Proc. Natl. Acad. Sci. U.S.A. 105 (20), 7252-7256
Gene SymbolACVR1C
Gene Full NameActivin A receptor, type IC
Alias SymbolsALK7, ACVRLK7
NCBI Gene Id130399
Protein NameActivin receptor type-1C
Description of TargetACVR1C is a type I receptor for the TGFB family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors.ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM].
Uniprot IDQ8NER5
Protein Accession #NP_660302
Nucleotide Accession #NM_145259
Protein Size (# AA)493
Molecular Weight55kDa
Protein InteractionsHSP90AA1; TDGF1; INHBB;
  1. What is the species homology for "ACVR1C Antibody - N-terminal region (ARP52836_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit".

  2. How long will it take to receive "ACVR1C Antibody - N-terminal region (ARP52836_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "ACVR1C Antibody - N-terminal region (ARP52836_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "ACVR1C Antibody - N-terminal region (ARP52836_P050)"?

    This target may also be called "ALK7, ACVRLK7" in publications.

  5. What is the shipping cost for "ACVR1C Antibody - N-terminal region (ARP52836_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "ACVR1C Antibody - N-terminal region (ARP52836_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "ACVR1C Antibody - N-terminal region (ARP52836_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "55kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "ACVR1C Antibody - N-terminal region (ARP52836_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "ACVR1C"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ACVR1C"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ACVR1C"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ACVR1C"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ACVR1C"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ACVR1C"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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