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Catalog No: OPCD01064
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OPCD01064
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Datasheets/ManualsPrintable datasheet for ACVR1 Recombinant Protein (OPCD01064)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Ile208-Lys340
::Subcellular Location: Membrane; Single-pass type I membrane prote
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity> 95%
SourceE.coli
TagN-terminal His and GST Tag
Gene SymbolACVR1
Gene Full Nameactivin A receptor type 1
Alias Symbolsactivin A receptor, type I;activin A receptor, type II-like kinase 2;activin receptor type I;activin receptor type-1;activin receptor-like kinase 2;ACTRI;ACVR1A;ACVRLK2;ALK2;FOP;hydroxyalkyl-protein kinase;serine/threonine-protein kinase receptor R1;SKR1;TGF-B superfamily receptor type I;TSRI.
NCBI Gene Id90
Protein NameActivin receptor type-1
Description of TargetOn ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin. May be involved for left-right pattern formation during embryogenesis (By similarity).
Uniprot IDQ04771
Protein Accession #NP_001096.1
Nucleotide Accession #NM_001105.4
Protein Size (# AA)Ile208~Lys340
Molecular Weight44kDa
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