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| Datasheets/Manuals | Printable datasheet for anti-ACTN1 (OASG00185) antibody |
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| Predicted Species Reactivity | Human, Mouse, Rat |
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| Product Format | Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Application | WB, IHC |
| Reconstitution and Storage | Store at -20C. Avoid repeated freeze/thaw cycles. |
| Immunogen | Synthesized peptide derived from the N-terminal region of human Actinin- Alpha1/2/3/4. Location: 40-120aa. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Specificity | Actinin- Alpha1/2/3/4 Polyclonal Antibody detects endogenous levels of Actinin- Alpha1/2/3/4 protein. |
| Application Info | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; |
| Gene Symbol | ACTN1, ACTN2, ACTN3, ACTN4 |
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| Gene Full Name | actinin, alpha 1 |
| Alias Symbols | BDPLT15 |
| NCBI Gene Id | 87; 88; 89; 81; 109711; 11472; 11474; 60595; 81634; 63836 |
| Description of Target | Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. |
| Uniprot ID | P12814, P35609, Q08043, O43707, Q7TPR4, Q9JI91, O88990, P57780, Q9Z1P2, Q9QXQ0 |
| Molecular Weight | 75 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "ACTN1 Antibody - N-terminal region (OASG00185)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".
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How long will it take to receive "ACTN1 Antibody - N-terminal region (OASG00185)"?
This item is available "Domestic: within 2-3 weeks delivery | International: 2-3 weeks".
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What buffer format is "ACTN1 Antibody - N-terminal region (OASG00185)" provided in?
This item is provided in "Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "ACTN1 Antibody - N-terminal region (OASG00185)"?
This target may also be called "BDPLT15" in publications.
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What is the shipping cost for "ACTN1 Antibody - N-terminal region (OASG00185)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "ACTN1 Antibody - N-terminal region (OASG00185)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "ACTN1 Antibody - N-terminal region (OASG00185)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "75 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "ACTN1 Antibody - N-terminal region (OASG00185)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "ACTN1, ACTN2, ACTN3, ACTN4"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "ACTN1, ACTN2, ACTN3, ACTN4"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "ACTN1, ACTN2, ACTN3, ACTN4"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "ACTN1, ACTN2, ACTN3, ACTN4"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "ACTN1, ACTN2, ACTN3, ACTN4"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "ACTN1, ACTN2, ACTN3, ACTN4"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.