Size:100 ul
$315.00
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SKU
OACA02417
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More Information
Predicted Species Reactivity Human
Product Format Liquid
Clonality Polyclonal
Isotype IgG
Host Rabbit
Application WB, IHC, CHIP
Reconstitution and Storage Store at 4C for up to one month. For long term storage, aliquot and store at -20C or -80C. Avoid freeze thaw cycles.
Replacement Item This antibody may replace item sc-118664 from Santa Cruz Biotechnology.
Immunogen Recombinant human Actin-like protein 6A protein(1-280aa)
Purification Antigen Affinity Purified
Predicted Homology Based on Immunogen Sequence Human, Mouse
Datasheets/Manuals Printable datasheet for anti-ACTL6A (OACA02417) antibody
Specificity Human
Formulation Provided in PBS, pH 7.3, 50% Glycerol, 0.02% Sodium Azide
Application Data WB:1:500-5000, IHC:1:20-1:200
Target Reference [1] N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB. Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A., Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E., Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454 (2012).
[2] Subunit organization of the human INO80 chromatin remodeling complex: An evolutionarily conserved core complex catalyzes ATP-dependent nucleosome remodeling. Chen L., Cai Y., Jin J., Florens L., Swanson S.K., Washburn M.P., Conaway J.W., Conaway R.C.J. Biol. Chem. 286:11283-11289 (2011).
[3] Initial characterization of the human central proteome. Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.BMC Syst. Biol. 5:17-17 (2011).
Gene Symbol ACTL6A
Official Gene Full Name actin like 6A
Alias Symbols Arp4, ACTL6, BAF53A, INO80K, ARPN-BETA
NCBI Gene Id 86
Protein Name actin-like protein 6A
Description of Target This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.
Swissprot Id O96019
Protein Accession # NP_004292.1
Nucleotide Accession # NM_004301.4
Protein Size (# AA) 429
Molecular Weight 47 kDa
Tissue Tool Find tissues and cell lines supported by DNA array analysis to express ACTL6A.
RNA Seq Find tissues and cell lines supported by RNA-seq analysis to express ACTL6A.
  1. What is the species homology for "ACTL6A Antibody (OACA02417)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human".

  2. How long will it take to receive "ACTL6A Antibody (OACA02417)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks".

  3. What buffer format is "ACTL6A Antibody (OACA02417)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "ACTL6A Antibody (OACA02417)"?

    This target may also be called "Arp4, ACTL6, BAF53A, INO80K, ARPN-BETA" in publications.

  5. What is the shipping cost for "ACTL6A Antibody (OACA02417)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "ACTL6A Antibody (OACA02417)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "ACTL6A Antibody (OACA02417)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "47 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "ACTL6A Antibody (OACA02417)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data tab on the product page.

  10. What are positive controls for "ACTL6A"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ACTL6A"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ACTL6A"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ACTL6A"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ACTL6A"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ACTL6A"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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