Catalog No: OPPA02416 (Formerly GWB-853173)
Size:1UG
Price: $75.00
SKU
OPPA02416
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Activin-A Protein (OPPA02416)

Datasheets/ManualsPrintable datasheet for OPPA02416
Product Info
Predicted Species ReactivityHuman
Product FormatActive form Activin-A was lyophilized from a concentrated 1mg/ml protein solution containing 50mM Tris-HCl pH-7.4 Physical appearance: Lyophilized freeze dried powder.
HostNicotiana Benthamiana
Additional InformationSolubility: INHBA protein should be reconstituted in distilled water to a concentration of 50 ug /ml. Due to the protein nature, dimmers and multimers may be observed.
::Biological Activity: The biological activity of INHBA is measured by its ability to inhibit mouse plasmacytoma cell line (MPC-11) cells proliferation ([3H]thymidine incorporation). ED50 5 ng/ml, corresponding to a specific activity of 200,000 units/mg.
::Product Introduction: Activins are homodimers or heterodimers of the different beta subunit isoforms, part of the TGFbeta family. Mature Activin A has two 116 amino acids residues betaA subunits (betaA-betaA). Activin displays an extensive variety of biological activities, including mesoderm induction, neural cell differentiation, bone remodelling, haematopoiesis, and reproductive physiology. Activins takes part in the production and regulation of hormones such as FSH, LH, GnRH and ACTH. Cells that are identified to express Activin A include fibroblasts, endothelial cells, hepatocytes, vascular smooth muscle cells, macrophages, keratinocytes, osteoclasts, bone marrow monocytes, prostatic epithelium, neurons, chondrocytes, osteoblasts, Leydig cells, Sertoli cells, and ovarian granulosa cells.
Product Description: Active form Activin-A Human Recombinant produced in Plant is a single homodimeric, glycosylated, polypeptide chain containing 2 x 116 amino acids and having a molecular weight of 27.4kDa.The Active form Activin-A is fused to a 6-His tag at N-terminus and purified by standard chromatographic techniques.
Reconstitution and StorageFor long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Repeated freezing and thawing is not recommended.
PurityGreater than 98% as obsereved by SDS-PAGE.
Peptide SequenceHHHHHHGLEC DGKVNICCKK QFFVSFKDIG WNDWIIAPSG YHANYCEGEC PSHIAGTSGS SLSFHSTVIN HYRMRGHSPF ANLKSCCVPT KLRPMSMLYY DDGQNIIKKD IQNMIVEECG CS.
Gene SymbolActivin A Active
Alias SymbolsEDF, FRP
NCBI Gene Id3624
Protein NameInhibin beta A chain
Description of TargetRecombinant Human Activin-A Active
Uniprot IDP08476
Protein Accession #NP_002183.1
Protein Size (# AA)Active|Recombinant
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