ACTA2 Antibody (OAAJ02283)

Catalog No: OAAJ02283

Size:100 ul

Western blot analysis on JK using alpha-SMA antibody, The lane on the left is blocked with the antigen-specific peptide.

Product Info

• Predicted Species Reactivity: Human, Mouse, Rat
• Product Format: Liquid. Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 C.Stable for 15 months from date of receipt
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB, IHC, IF
• Reconstitution and Storage: Store at -20C. Stable for 12 months from date of receipt.
• Immunogen: Synthetic peptide corresponding to N terminal residues of Human alpha smooth muscle Actin.
• Concentration: 1 mg/ml
• Specificity: alpha-SMA antibody detects endogenous levels of alpha-SMA.
• Application Info: WB: 1:500~1:1000, IHC: 1:200, IF: 1:200,

Target Info

• Gene Symbol: ACTA2
• Gene Full Name: actin, alpha 2, smooth muscle, aorta
• Alias Symbols: ACTSA
• NCBI Gene Id: 59
• Description of Target: Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. AATs are characterized by permanent dilation of the thoracic aorta usually due to degenerative changes in the aortic wall. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance.
• Uniprot ID: P62736
• Molecular Weight: 45 kDa