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Catalog No: OAGA04026
Size:100 ul
Price: $466.00
SKU
OAGA04026
Availability: Domestic: within 1-2 week delivery | International: 1-2 weeks
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for OAGA04026
Product Info
Predicted Species ReactivityHuman, Mouse, Rat
Product FormatLiquid 1X PBS, 20% glycerol (pH 7) with 0.025% Proclin300 added as a preservative
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ApplicationICC, IF, IHC-P, WB
Reconstitution and StorageKeep as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze/thaw cycles.
ImmunogenRecombinant protein encompassing a sequence within the N-terminus region of human ATP citrate lyase. The exact sequence is proprietary.
PurificationPurified by antigen-affinity chromatography.
ConcentrationVaries by lot. See vial for concentration.
Application InfoWB: 1:1000~10000
ICC/IF: 1:100~1000
IHC-P: 1:100~1000
Publications

ATP-citrate lyase promotes axonal transport across species. Nat Commun. 12, 5878 (2021)

Description
Gene SymbolACLY
Gene Full NameATP citrate lyase
Alias SymbolsACL, ATPCL, CLATP
NCBI Gene Id47
Protein NameATP-citrate synthase
Description of TargetATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
Uniprot IDP53396
Protein Accession #NP_001087.2
Nucleotide Accession #NM_001096.2
Molecular Weight121 kDa
  1. What is the species homology for "ACLY Antibody - N-terminal region (OAGA04026)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Rat".

  2. How long will it take to receive "ACLY Antibody - N-terminal region (OAGA04026)"?

    This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".

  3. What buffer format is "ACLY Antibody - N-terminal region (OAGA04026)" provided in?

    This item is provided in "Liquid 1X PBS, 20% glycerol (pH 7) with 0.025% Proclin300 added as a preservative".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "ACLY Antibody - N-terminal region (OAGA04026)"?

    This target may also be called "ACL, ATPCL, CLATP" in publications.

  5. What is the shipping cost for "ACLY Antibody - N-terminal region (OAGA04026)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "ACLY Antibody - N-terminal region (OAGA04026)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "ACLY Antibody - N-terminal region (OAGA04026)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "121 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "ACLY Antibody - N-terminal region (OAGA04026)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "ACLY"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ACLY"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ACLY"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ACLY"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ACLY"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ACLY"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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