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Catalog No: OAAB20905
Size:100ul
Price: $450.00
SKU
OAAB20905
Availability: Domestic: within 1-2 week delivery | International: within 1-2 week delivery
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  • $55: Antibody & Protein in US
  • $55 + $25/Kit in US
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Datasheets/ManualsPrintable datasheet for anti-ACLY (OAAB20905) antibody
Product Info
Predicted Species ReactivityHuman, Mouse
Product FormatLiquid
ClonalityMonoclonal
HostRabbit
ApplicationWB, ICC, FC
Additional InformationFunction: ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine.
Reconstitution and StorageMaintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Predicted Homology Based on Immunogen SequenceHuman, Mouse
Preservative0.02% Sodium Azide and 50% glycerol
FormulationPurified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol
Application InfoWB: 1:1000
ICC: 1:150
FC: 1:100
ReferenceElshourbagy N.A.,et al.Eur. J. Biochem. 204:491-499(1992).
Lord K.A.,et al.Protein Expr. Purif. 9:133-141(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Potapova I.A.,et al.Biochemistry 39:1169-1179(2000).
Gene SymbolACLY
Gene Full NameATP citrate lyase
Alias SymbolsACL, ATPCL, CLATP
NCBI Gene Id47
Description of TargetATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
Uniprot IDP53396
Protein Accession #NP_001087.2
Nucleotide Accession #NM_001096.2
Molecular Weight121 kDa
  1. What is the species homology for "ACLY Antibody - C-terminal region (OAAB20905)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse".

  2. How long will it take to receive "ACLY Antibody - C-terminal region (OAAB20905)"?

    This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".

  3. What buffer format is "ACLY Antibody - C-terminal region (OAAB20905)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "ACLY Antibody - C-terminal region (OAAB20905)"?

    This target may also be called "ACL, ATPCL, CLATP" in publications.

  5. What is the shipping cost for "ACLY Antibody - C-terminal region (OAAB20905)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "ACLY Antibody - C-terminal region (OAAB20905)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "ACLY Antibody - C-terminal region (OAAB20905)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "121 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "ACLY Antibody - C-terminal region (OAAB20905)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "ACLY"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ACLY"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ACLY"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ACLY"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ACLY"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ACLY"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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