ACE2 Antibody : HRP (OAPB00220-HRP)

Catalog No: OAPB00220-HRP

Size:0.1 mg

Product Info

• Predicted Species Reactivity: Human
• Product Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: HRP: Horseradish Peroxidase
• Application: ELISA, WB, IHC
  Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
• Reconstitution and Storage: All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
• Immunogen: The immunogen for anti-ACE2 antibody: antibody was raised against a synthetic peptide corresponding to amino acids near the center of human ACE2.
• Purification: Affinity chromatography purified via peptide column
• Predicted Homology Based on Immunogen Sequence: Human
• Concentration: 0.6-0.7 mg/ml
• Blocking Peptide: For anti-ACE2 antibody is Catalog # OEPB02314
• Specificity: Anti-ACE2 has no cross response to ACE1.
• Application Info: ACE2 antibody can be used for the detection of ACE2 by Western blot at 0.5 to 2 ug/ml. A 90 kDa band can be detected. Anti-ACE2 has no cross response to ACE1. (Optimal dilution should be determined by user)
• Reference: Donoghue M, Hsieh F, Baronas E, et al. A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotension I to angiotension 1-9. Circ. Res. 2000;87:1-9.;Tipnis SR, Hooper NM, Hyde R, et al. A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase. J Biol. Chem. 2000;275:33238-43.;Li W, Moore MJ, Vasileva N, et al. Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus. Nature 2003;426:450-4.
  ;Crackower MA, Sarao R, Oudit GY, et al. Angiotensin-converting enzyme 2 is an essential regulator of heart function. Nature 2002;417:822-8.
  

Target Info

• Gene Symbol: ACE2
• Alias Symbols: ACEH
• NCBI Gene Id: 59272
• Protein Name: Angiotensin-converting enzyme 2
• Description of Target: (IN2) Angiotensin-converting enzyme 2, SARS receptor
• Uniprot ID: Q9BYF1
• Protein Accession #: NP_068576