ACD Antibody (OAAL00798)

Catalog No: OAAL00798

Size:100UG

Western Blot analysis of ACD expression in transfected 293T cell line by ACD monoclonal antibody (M01), clone 1C11-1A7.
Lane 1: ACD transfected lysate (Predicted MW: 57.7 KDa).
Lane 2: Non-transfected lysate.

Detection limit for recombinant GST tagged ACD is 1 ng/ml as a capture antibody.

Immunoprecipitation of ACD transfected lysate using anti-ACD monoclonal antibody and Protein A Magnetic Bead and immunoblotted with ACD MaxPab rabbit polyclonal antibody.

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: Liquid
• Clonality: Monoclonal
• Clone: 1C11-1A7
• Isotype: IgG1 Kappa
• Host: Mouse
• Application: Enzyme-linked immunosorbent assay|Immunoprecipitation|Western blot
• Reconstitution and Storage: Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
• Immunogen: ACD (AAH16904, 1 a.a. ~ 544 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Peptide Sequence: MPGRCQSDAAMRVNGPASRAPAGWTSGSLHTGPRAGRPRAQARGVRGRGLLLRPRPAKELPLPRKGGAWAPAGNPGPLHPLGVAVGMAGSGRLVLRPWIRELILGSETPSSPRAGQLLEVLQDAEAAVAGPSHAPDTSDVGATLLVSDGTHSVRCLVTREALDTSDWEEKEFGFRGTEGRLLLLQDCGVHVQVAEGGAPAEFYLQVDRFSLLPTEQPRLRVPGCNQDLDVQKKLYDCLEEHLSESTSSNAGLSLSQLLDEMREDQEHQGALVCLAESCLTLEGPCTAPPVTHWAASRCKATGEAVYTVPSSMLCISENDQLILSSLGPCQRTQGPELPPPDPALQDLSLTLIASPPSSPSSSGTPALPGHMSSEESGTSISLLPALSLAAPDPGQRSSSQPSPAICSAPATLTPRSPHASRTPSSPLQSCTPSLSPRSHVPSPHQALVTRPQKPSLEFKEFVGLPCKNRPPFPRTGATRGAQEPCSVWEPPKRHRDGSAFQYEYEPPCTSLCARVQAARLPPQLMAWALHFLMDAQPGSEPTPM
• Formulation: In 1x PBS, pH 7.4

Target Info

• Gene Symbol: ACD
• Gene Full Name: ACD shelterin complex subunit and telomerase recruitment factor
• Alias Symbols: adrenocortical dysplasia homolog;adrenocortical dysplasia protein homolog;PIP1;POT1 and TIN2-interacting protein;PTOP;TIN2 interacting protein 1;TINT1;TPP1.
• NCBI Gene Id: 65057
• Protein Name: ACD protein [Homo sapiens]|Homo sapiens adrenocortical dysplasia homolog (mouse), mRNA (cDNA clone MGC:21034 IMAGE:4400396), complete cds
• Description of Target: This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I. [provided by RefSeq
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/AAH16904
• Nucleotide Accession #: https://www.ncbi.nlm.nih.gov/nuccore/BC016904