ACAN Antibody (Cleaved-Asp369) (OASG00236)

Catalog No: OASG00236

Size:100 uL

Product Info

• Predicted Species Reactivity: Human, Rat
• Product Format: Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
• Clonality: Polyclonal
• Isotype: IgG
• Host: Rabbit
• Application: WB, IHC
• Reconstitution and Storage: Store at -20C. Avoid repeated freeze/thaw cycles.
• Immunogen: Synthesized peptide derived from the N-terminal region of human Aggrecan. Location: 290-370aa.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Concentration: 1 mg/ml
• Target Post-Translational Modification: Cleaved-Asp369
• Specificity: Cleaved-Aggrecan (D369) Polyclonal Antibody detects endogenous levels of fragment of activated Aggrecan protein resulting from cleavage adjacent to D369.
• Application Info: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000;

Target Info

• Gene Symbol: ACAN
• Gene Full Name: aggrecan
• Alias Symbols: AGC1, SEDK, AGCAN, CSPG1, MSK16, CSPGCP, SSOAOD
• NCBI Gene Id: 176; 58968
• Description of Target: This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene.
• Uniprot ID: P16112, P07897
• Molecular Weight: 44/72 kDa