ABI1 Antibody - C-terminal region (ARP63430_P050)

Catalog No: ARP63430_P050

WB Suggested Anti-ABI1 Antibody
Titration: 1.0 ug/ml
Positive Control: 721_B Whole CellABI1 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
• Peptide Sequence: Synthetic peptide located within the following region: IEKVVAIYDYTKDKDDELSFMEGAIIYVIKKNDDGWYEGVCNRVTGLFPG
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-ABI1 (ARP63430_P050) antibody is Catalog # AAP63430
• Sample Type Confirmation:

  ABI1 is strongly supported by BioGPS gene expression data to be expressed in 721_B

Target Info

• Gene Symbol: ABI1
• Gene Full Name: Abl-interactor 1
• Alias Symbols: E3B1, ABI-1, ABLBP4, NAP1BP, SSH3BP, SSH3BP1
• NCBI Gene Id: 10006
• Protein Name: Abl-interactor 1 variant 72 EMBL ACJ12785.1
• Description of Target: This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14.
• Uniprot ID: B6VEX5
• Protein Accession #: NP_001171595
• Nucleotide Accession #: NM_001178124
• Protein Size (# AA): 388
• Molecular Weight: 42kDa
• Protein Interactions: ABL1; UBC; PRPF40A; TCERG1; GAS7; APBB1; SRRM1; PRKAA1; PIK3R1; CDC123; CTTN; NCK2; NCK1; CBL; CACNA1A; RYK; EPS8L1; ENAH; MINK1; EVL; NIN; CYFIP2; HSPA8; WASF2; WASF1; PAK2; NCKAP1; ABI1; VASP; SOS2; EPS8; NCF1; SPTA1; SPTAN1; SOS1; NEB; EPS8L3; EPS8L2;