ABCG5 Recombinant Protein (OPCD00155)

Catalog No: OPCD00155

ABCG5 Recombinant Protein (OPCD00155) using SDS-PAGE

ABCG5 Recombinant Protein (OPCD00155) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Mouse|Mus musculus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Asp66-Gly276
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His Tag

Target Info

• Gene Symbol: Abcg5
• Gene Full Name: ATP binding cassette subfamily G member 5
• Alias Symbols: ATP-binding cassette sub-family G member 5;ATP-binding cassette, sub-family G (WHITE), member 5;cm;cmp;Ster;sterolin 1;sterolin-1;tr;trac.
• NCBI Gene Id: 27409
• Protein Name: ATP-binding cassette sub-family G member 5
• Description of Target: ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+)- and ATP-dependent sterol transport across the cell membrane (PubMed:16352607, PubMed:16867993, PubMed:18402465). Plays an essential role in the selective transport of dietary plant sterols and cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (PubMed:12444248, PubMed:14504269, PubMed:14657202, PubMed:19846887, PubMed:25378657). Required for normal sterol homeostasis (PubMed:12444248, PubMed:14657202). The heterodimer with ABCG8 has ATPase activity (PubMed:16352607, PubMed:16867993).
• Uniprot ID: Q99PE8
• Protein Accession #: NP_114090.1
• Nucleotide Accession #: NM_031884.2
• Protein Size (# AA): Asp66~Gly276
• Molecular Weight: 30&27kDa