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Catalog No: OPCD00788
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OPCD00788
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Datasheets/ManualsPrintable datasheet for ABCC11 Recombinant Protein (OPCD00788)
Product Info
Predicted Species ReactivityHomo sapiens|Human
Product FormatFreeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
HostE.coli
ConjugationUnconjugated
ApplicationPositive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
Additional InformationEndotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
::Residues: Ile1141-Arg1382
Reconstitution and Storage2°C to 8°C|-80°C
Concentration200 ug/mL (prior to lyoph)
Purity>90%
SourceE.coli
TagN-terminal His Tag
Gene SymbolABCC11
Gene Full NameATP binding cassette subfamily C member 11
Alias SymbolsATP-binding cassette protein C11;ATP-binding cassette sub-family C member 11;ATP-binding cassette transporter MRP8;ATP-binding cassette transporter sub-family C member 11;ATP-binding cassette, sub-family C (CFTR/MRP), member 11;EWWD;MRP8;multidrug resistance-associated protein 8;multi-resistance protein 8;WW.
NCBI Gene Id85320
Protein NameATP-binding cassette sub-family C member 11
Description of TargetParticipates in physiological processes involving bile acids, conjugated steroids and cyclic nucleotides (PubMed:12764137, PubMed:15537867). Enhances the cellular extrusion of cAMP and cGMP (PubMed:12764137, PubMed:15537867). Stimulates the ATP-dependent uptake of a range of physiological and synthetic lipophilic anions, including the glutathione S-conjugates leukotriene C4 and dinitrophenyl S-glutathione, steroid sulfates such as dehydroepiandrosterone 3-sulfate (DHEAS) and estrone 3-sulfate, glucuronides such as estradiol 17-beta-D-glucuronide (E(2)17betaG), the monoanionic bile acids glycocholate and taurocholate, and methotrexate (PubMed:15537867, PubMed:25896536). Probably functions to secrete earwax (PubMed:16444273, PubMed:19383836). Required for the secretion of components contributing to axillary odor formation (PubMed:19710689).
Uniprot IDQ96J66
Protein Accession #NP_115972.2
Nucleotide Accession #NM_032583.3
Protein Size (# AA)Ile1141~Arg1382
Molecular Weight31kDa
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