A1M Recombinant Protein (OPCD06561)

Catalog No: OPCD06561

A1M Recombinant Protein (OPCD06561) using SDS-PAGE

A1M Recombinant Protein (OPCD06561) using SDS-PAGE

Product Info

• Predicted Species Reactivity: Rat|Rattus norvegicus
• Product Format: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
• Host: E.coli
• Conjugation: Unconjugated
• Application: Positive control|Sodium sodecyl sulfate - polyacrylamide gel electrophoresis|Western blot
• Additional Information: Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method)
  Residues: Leu1251-Ala1500
• Reconstitution and Storage: 2°C to 8°C|-80°C
• Concentration: 200 ug/mL (prior to lyoph)
• Purity: > 95%
• Source: E.coli
• Tag: N-terminal His and GST Tag

Target Info

• Gene Symbol: Pzp
• Gene Full Name: pregnancy-zone protein
• Alias Symbols: A1m;alpha-1-M;alpha-1-macroglobulin;alpha-1-macroglobulin 165 kDa subunit.
• NCBI Gene Id: 252922
• Protein Name: Alpha-1-macroglobulin
• Description of Target: Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase (By similarity).
• Uniprot ID: Q63041
• Protein Accession #: NP_665722.2
• Nucleotide Accession #: NM_145779.2
• Protein Size (# AA): Leu1251~Ala1500
• Molecular Weight: 57kDa