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2023 DDN Webinar: High Throughput Antibody Characterization

Using High-Throughput Surface Plasmon Resonance for In-Depth Antibody Characterization

Antibody-based therapeutics are central to drug discovery but present significant analytical challenges due to their complex and heterogeneous nature. Surface Plasmon Resonance (SPR) is ideal for analyzing antibodies, measuring binding kinetics, and performing epitope binning and mapping, which is essential for developing high-precision ELISA or multiplex assays. Aviva Systems Biology leverages decades of expertise in antibodies and ELISA, combined with the innovative Carterra LSA, to offer high-throughput antibody characterization services.

Webinar Highlights:

  • In-Depth Analysis: Learn how HT-SPR can measure antibody-antigen binding kinetics with high precision.
  • Epitope Binning & Mapping: Discover the power of high-resolution competition-based epitope binning to characterize diverse monoclonal antibody panels quickly and effectively.
  • Real-World Applications: Understand how epitope mapping identifies antibody pairs for developing high-precision ELISA or multiplex assays.
  • Interested in antibody characterization in your own work?

  • High throughput: Kinetically screen and rank up to 1,152 mAbs, 384 clones at one time in parallel
  • Low sample usage: Only < 200µl of each interactant.
  • Rapid data analysis: Powerful software tools enable large data-sets to be rapidly fitted and visualized and automatically validated against several data quality parameters
  • Detailed data mining: Interrogate mAb panels via interactive on-rate, off-rate, affinity and iso-affinity plots
  • Data integration: Combine binning and kinetics screening data for un-paralleled mAb evaluation
  • About Aviva Systems Biology

    Founded in 2002, Aviva Systems Biology supports scientists in their basic research, preclinical, drug development, and diagnostics workflows. With an extensive portfolio of nearly 500,000 products for antibodies, proteins, and immunoassays and over 20 years of expertise in antibody and protein production, scientists can find the unique reagents and support they need for success in their work.

    Meet the Experts:

    Kevin Harvey, PhD President of Aviva Systems Biology

    Daniel Bedinger, PhD Head of Applications Science at Carterra