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Catalog No: OASG04135
Size:100 uL
Price: $239.00
SKU
OASG04135
Availability: Domestic: within 2-3 weeks delivery | International: 2-3 weeks
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XRCC5 Antibody (Phospho-Thr714) (OASG04135)

Datasheets/ManualsPrintable datasheet for anti-XRCC5 (OASG04135) antibody
Product Info
Predicted Species ReactivityHuman, Monkey
Product FormatLiquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ApplicationWB, IHC, IF
Reconstitution and StorageStore at -20C. Avoid repeated freeze/thaw cycles.
ImmunogenSynthesized peptide derived from human Ku-80 around the phosphorylation site of T714. Location: 660-740aa.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration1 mg/ml
Target Post-Translational ModificationPhospho-Thr714
SpecificityPhospho-Ku-80 (T714) Polyclonal Antibody detects endogenous levels of Ku-80 protein only when phosphorylated at T714.
Application InfoWB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000;
Gene SymbolXRCC5
Gene Full NameX-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
Alias SymbolsKU80, KUB2, Ku86, NFIV, KARP1, KARP-1
NCBI Gene Id7520;
Description of TargetThe protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Uniprot IDP13010
Molecular Weight83 kDa
  1. What is the species homology for "XRCC5 Antibody (Phospho-Thr714) (OASG04135)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Monkey".

  2. How long will it take to receive "XRCC5 Antibody (Phospho-Thr714) (OASG04135)"?

    This item is available "Domestic: within 2-3 weeks delivery | International: 2-3 weeks".

  3. What buffer format is "XRCC5 Antibody (Phospho-Thr714) (OASG04135)" provided in?

    This item is provided in "Liquid. 1 mg/mL in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "XRCC5 Antibody (Phospho-Thr714) (OASG04135)"?

    This target may also be called "KU80, KUB2, Ku86, NFIV, KARP1, KARP-1" in publications.

  5. What is the shipping cost for "XRCC5 Antibody (Phospho-Thr714) (OASG04135)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "XRCC5 Antibody (Phospho-Thr714) (OASG04135)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "XRCC5 Antibody (Phospho-Thr714) (OASG04135)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "83 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "XRCC5 Antibody (Phospho-Thr714) (OASG04135)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "XRCC5"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "XRCC5"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "XRCC5"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "XRCC5"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "XRCC5"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "XRCC5"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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