XRCC5 Antibody (OAEC04810)

Catalog No: OAEC04810

Size:100 ug/100 ul

Western blot analysis using XRCC5 mouse mAb against Hela (1), MCF-7 (2), A549 (3) and NIH/3T3 (4) cell lysate.

Immunohistochemical analysis of paraffin-embedded human tonsil tissues (left) and human colon cancer tissues (right) using XRCC5 mouse mAb with DAB staining.

ELISA Result

Product Info

• Predicted Species Reactivity: Human, Mouse
• Product Format: Ascitic fluid containing 0.03% sodium azide
• Clonality: Monoclonal
• Clone: 5C5
• Isotype: IgG1
• Host: Mouse
• Reconstitution and Storage: Store at 4C, for long term storage, store at -20C.
• Immunogen: Purified recombinant fragment of human XRCC5 expres sed in EColi.
• Concentration: 1 mg/ml
• Application Info: WB: 1/500 - 1/2000
  IHC: 1/200 - 1/1000
  IF: 1/200 - 1/1000
  FC: 1/200 - 1/400
  ELISA: 1/10000
  

Target Info

• Gene Symbol: XRCC5
• Gene Full Name: X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
• Alias Symbols: KU80, KUB2, Ku86, NFIV, KARP1, KARP-1
• NCBI Gene Id: 7520
• Description of Target: The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events . This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination.
• Uniprot ID: P13010
• Molecular Weight: 86 kDa