TPR Antibody - C-terminal region (ARP61102_P050)

Catalog No: ARP61102_P050

WB Suggested Anti-TPR Antibody
Titration: 1.0 ug/ml
Positive Control: Fetal Lung

Rabbit Anti-TPR Antibody
Catalog Number: ARP61102_P050
Formalin Fixed Paraffin Embedded Tissue: Human Heart Tissue
Observed Staining: Nucleus in cardiomyocytes
Primary Antibody Concentration: 1:100
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB, IHC
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TPR
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
• Peptide Sequence: Synthetic peptide located within the following region: SSEAGLEIDSQQEEEPVQASDESDLPSTSQDPPSSSSVDTSSSQPKPFRR
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-TPR (ARP61102_P050) antibody is Catalog # AAP61102 (Previous Catalog # AAPP47266)

Target Info

• Gene Symbol: TPR
• Gene Full Name: Translocated promoter region, nuclear basket protein
• Alias Symbols: -
• NCBI Gene Id: 7175
• Protein Name: Nucleoprotein TPR
• Description of Target: This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias.
• Uniprot ID: P12270
• Protein Accession #: NP_003283
• Nucleotide Accession #: NM_003292
• Protein Size (# AA): 2363
• Molecular Weight: 267kDa
• Protein Interactions: STAU1; UBC; LGR4; MDM2; MAD1L1; EED; NPM1; LMNA; HDAC9; ITGA4; FN1; CBX7; BUD31; TAF15; TOP1; SNRPD1; SNRPA1; SRSF5; SFPQ; S100A9; RPL37A; RPL18A; RPL6; RBM4; RAN; PRKDC; NHP2L1; SEPT2; IK; HRAS; HNRNPU; HNRNPA2B1; EEF1D; EEF1B2; DDX3X; DDX1; DDB1; CIRBP;