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Datasheets/Manuals | Printable datasheet for TOP2B Antibody (OAAF01970) |
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Predicted Species Reactivity | Human|Mouse |
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Product Format | Liquid |
Clonality | Polyclonal |
Host | Rabbit |
Application | Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot |
Reconstitution and Storage | -20°C |
Immunogen | The antiserum was produced against synthesized peptide derived from human TOP2B. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Specificity | Topoisomerase II β antibody detects endogenous levels of total topoisomerase II β protein. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Dilution | The optimal working dilution should be determined by the end user. |
Application Info | WB: 1:500~1:3000; IHC: 1:50~1:100; ELISA: 1:20000 |
Reference | René M. Linka, Nucleic Acids Res., May 2007; 10.1093. John R. Jenkins, Nucleic Acids Res., Nov 1992; 20: 5587 - 5592. Kathryn L. Gilroy, Nucleic Acids Res., Mar 2006; 34: 1597 - 1607. Sophie Dereuddre, Cancer Res., Oct 1997; 57: 4301 - 4308. |
Gene Symbol | TOP2B |
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Gene Full Name | DNA topoisomerase II beta |
Alias Symbols | antigen MLAA-44;DNA topoisomerase 2-beta;DNA topoisomerase II, 180 kD;DNA topoisomerase II, beta isozyme;top2beta;TOPIIB;topo II beta;topoisomerase (DNA) II beta 180kDa;topoisomerase II beta;topoisomerase IIb;U937 associated antigen. |
NCBI Gene Id | 7155 |
Protein Name | DNA topoisomerase 2-beta |
Description of Target | Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. |
Uniprot ID | Q02880 |
Protein Accession # | NP_001059.2 |
Molecular Weight | 183 kDa |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "TOP2B Antibody (OAAF01970)"?
The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse".
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How long will it take to receive "TOP2B Antibody (OAAF01970)"?
This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".
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What buffer format is "TOP2B Antibody (OAAF01970)" provided in?
This item is provided in "Liquid".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "TOP2B Antibody (OAAF01970)"?
This target may also be called "antigen MLAA-44;DNA topoisomerase 2-beta;DNA topoisomerase II, 180 kD;DNA topoisomerase II, beta isozyme;top2beta;TOPIIB;topo II beta;topoisomerase (DNA) II beta 180kDa;topoisomerase II beta;topoisomerase IIb;U937 associated antigen." in publications.
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What is the shipping cost for "TOP2B Antibody (OAAF01970)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "TOP2B Antibody (OAAF01970)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "TOP2B Antibody (OAAF01970)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "183 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "TOP2B Antibody (OAAF01970)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "TOP2B"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "TOP2B"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "TOP2B"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "TOP2B"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "TOP2B"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "TOP2B"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.