TLR5 Antibody (OAPB00362)

Catalog No: OAPB00362

Size:100UG

Western blot analysis of TLR5 in THP-1 cell lysate with TLR5 antibody at (A) 0.5, (B) 1 and (C) 2 μg/mL.

Immunofluorescence of TLR5 in THP1 cells with TLR5 antibody at 10 ug/mL.

Immunocytochemistry of TLR5 in THP-1 cells with TLR5 antibody at 10 μg/mL.

Product Info

• Predicted Species Reactivity: Human|Mouse
• Product Format: Liquid. TLR5 Antibody is supplied in PBS containing 0.02% sodium azide.
• Clonality: Polyclonal
• Host: Rabbit
• Conjugation: Unconjugated
• Application: Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Western blot
  Buffer: Antibody is supplied in PBS containing 0.02% sodium azide.
• Reconstitution and Storage: TLR5 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Immunogen: TLR5 antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of human TLR5. The immunogen is located within the last 50 amino acids of TLR5.
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Human; Mouse
• Concentration: 1 mg/ml
• Blocking Peptide: For anti-TLR5 antibody is Catalog # OEPB02465
• Application Info: TLR5 antibody can be used for detection of TLR5 by Western blot at 1 to 2 ug/ml. (Optimal dilution should be determined by user)
• Reference: Takeda K, Kaisho T, and Akira S. Toll-like receptors. Annu. Rev. Immunol.2003; 21:335-76.;Janeway CA Jr. and Medzhitov R. Innate immune recognition. Annu. Rev. Immunol.2002; 20:197-216.;McGettrick AF and O’Neill LAJ. The expanding family of MyD88-like adaptors in Toll-like receptor signal transduction. Mol Imm.2004; 41:577-82.;Hayashi F, Smith KD, Ozinsky A, et al. The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. Nature2001; 410:1099-103.

Target Info

• Gene Symbol: TLR5
• Gene Full Name: toll like receptor 5
• Alias Symbols: MELIOS;SLE1;SLEB1;systemic lupus erythematosus susceptibility 1;TIL3;toll/interleukin-1 receptor-like protein 3;toll-like receptor 5.
• NCBI Gene Id: 7100
• Protein Name: Toll-like receptor 5|toll-like receptor 5 precursor [Homo sapiens]
• Description of Target: Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
• Uniprot ID: O60602
• Protein Accession #: https://www.ncbi.nlm.nih.gov/protein/NP_003259
• Molecular Weight: Predicted: 94 kDa Observed: 94 kDa