TLR2 Protein Lysate (GST tagged) (Expressed in bacteria) (200ug)

Catalog#: APL10196

• Size: 200ug

• Description of Target: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.
• Gene Symbol: TLR2
• Alias Symbols: TIL4; CD282
• Protein Accession#: NP_003255
• Nucleotide Accession#: NM_003264
• Swissprot Id: O60603
• Molecular Weight: 43
• Tag: GST in N-terminal
• Quality Control: This product was tested on western blot.
  Application : Western blot standard.
  Observed Molecular Weight: 42
  Expression system : Bacteria
• Reconstitution and Storage: Add 200ul of distilled water. Final concentration is 1 mg/ml. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
• Additional Information: Buffer Formulation: 0.1M Tris-HCl (pH 6.8) buffer containing 0.2M DTT, 4% SDS, 0.2% Bromophenol blue and 20% Sucrose.
• Key Reference: N/A