TGFBRAP1 Antibody - C-terminal region (OAAB09709)

Catalog No: OAAB09709

Size:400ul

TGFBRAP1 Antibody (C-term) (Cat. #OAAB09709) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the TGFBRAP1 antibody detected the TGFBRAP1 protein (arrow).

TGFBRAP1 Antibody (C-term) (Cat. #OAAB09709)immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TGFBRAP1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Product Info

• Predicted Species Reactivity: Human
• Product Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Clonality: Polyclonal
• Isotype: Ig
• Host: Rabbit
• Application: WB, IHC
• Additional Information: Precautions: TGFBRAP1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
  Function: Plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling. May recruit SMAD4 to the vicinity of the receptor complex and facilitate its interaction with receptor-regulated Smads, such as SMAD2
  Cellular Location: Cytoplasm. Note=Colocalizes with TGF-beta receptors in the absence of signaling
• Reconstitution and Storage: Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: This TGFBRAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 499-528 amino acids from the C-terminal region of human TGFBRAP1.
• Predicted Homology Based on Immunogen Sequence: Human
• Concentration: Approximately 0.5mg/ml. Actual concentration varies with each lot.
• Application Info: WB: 1:1000
  IHC-P: 1:10~50

Target Info

• Gene Symbol: TGFBRAP1
• Alias Symbols: VPS3, TRAP1, TRAP-1
• NCBI Gene Id: 9392
• Protein Name: Transforming growth factor-beta receptor-associated protein 1
• Description of Target: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
• Uniprot ID: Q8WUH2
• Protein Accession #: NP_001136093.1
• Molecular Weight: 97158 Da