Catalog No: ARP57917_P050
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ARP57917_P050
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Datasheets/ManualsPrintable datasheet for anti-TCF7L1 (ARP57917_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the N terminal region of human TCF7L1
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 86%; Dog: 86%; Human: 100%; Mouse: 86%; Rabbit: 86%; Rat: 86%
Peptide SequenceSynthetic peptide located within the following region: ESENQSSSSDSEAERRPQPVRDTFQKPRDYFAEVRRPQDSAFFKGPPYPG
Concentration0.5 mg/ml
Blocking PeptideFor anti-TCF7L1 (ARP57917_P050) antibody is Catalog # AAP57917 (Previous Catalog # AAPP32328)
ReferenceHillier,L.W., (2005) Nature 434 (7034), 724-731
Gene SymbolTCF7L1
Gene Full NameTranscription factor 7-like 1 (T-cell specific, HMG-box)
Alias SymbolsTCF3, TCF-3
NCBI Gene Id83439
Protein NameTranscription factor 7-like 1
Description of TargetTCF7L1 participates in the Wnt signaling pathway. It binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. It is necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. TCF7L1 down-regulates NQO1, leading to increased mitomycin c resistance.
Uniprot IDQ9HCS4
Protein Accession #NP_112573
Nucleotide Accession #NM_031283
Protein Size (# AA)588
Molecular Weight63kDa
Protein InteractionsUBC; mdfic; Mdfi; DAZAP2; CTNNB1;
  1. What is the species homology for "TCF7L1 Antibody - N-terminal region (ARP57917_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Rabbit".

  2. How long will it take to receive "TCF7L1 Antibody - N-terminal region (ARP57917_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "TCF7L1 Antibody - N-terminal region (ARP57917_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "TCF7L1 Antibody - N-terminal region (ARP57917_P050)"?

    This target may also be called "TCF3, TCF-3" in publications.

  5. What is the shipping cost for "TCF7L1 Antibody - N-terminal region (ARP57917_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "TCF7L1 Antibody - N-terminal region (ARP57917_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "TCF7L1 Antibody - N-terminal region (ARP57917_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "63kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "TCF7L1 Antibody - N-terminal region (ARP57917_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "TCF7L1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "TCF7L1"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "TCF7L1"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "TCF7L1"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "TCF7L1"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "TCF7L1"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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