Catalog No: OAAF04239 (Formerly GWB-ASE978)
Size:100 ug
Price: $344.00
SKU
OAAF04239
Availability: Domestic: within 1-2 week delivery | International: 1-2 weeks
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Datasheets/ManualsPrintable datasheet for STK24 Antibody (OAAF04239)
Product Info
Predicted Species ReactivityHuman|Mouse|Rat
Product FormatLiquid
ClonalityPolyclonal
HostRabbit
ApplicationEnzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Reconstitution and Storage-20°C
ImmunogenThe antiserum was produced against synthesized peptide derived from human STK24.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
SpecificitySTK24 antibody detects endogenous levels of total STK24 protein.
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
DilutionThe optimal working dilution should be determined by the end user.
Application InfoWB: 1:500~1:3000; IHC: 1:50~1:100; ELISA: 1:40000
ReferenceSchinkmann K., J. Biol. Chem. 272:28695-28703(1997).
Zhou T.-H., J. Biol. Chem. 275:2513-2519(2000).
Dunham A., Nature 428:522-528(2004).
Gene SymbolSTK24
Gene Full Nameserine/threonine kinase 24
Alias Symbolsepididymis secretory protein Li 95;HEL-S-95;mammalian STE20-like protein kinase 3;MST3;MST3B;serine/threonine kinase 24 (STE20 homolog, yeast);serine/threonine-protein kinase 24;STE20;STE20-like kinase 3;STE20-like kinase MST3;sterile 20-like kinase 3;STK3.
NCBI Gene Id8428
Protein NameSerine/threonine-protein kinase 24
Description of TargetSerine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on 'Thr-442' and stimulates its kinase activity. In association with STK26 negatively regulates Golgi reorientation in polarized cell migration upon RHO activation (PubMed:27807006). Regulates also cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates PTPN12 and inhibits its activity and may regulate PXN phosphorylation through PTPN12. May act as a key regulator of axon regeneration in the optic nerve and radial nerve.
Uniprot IDQ9Y6E0
Protein Accession #NP_001027467.2
Molecular Weight49 kDa
  1. What is the species homology for "STK24 Antibody (OAAF04239)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human|Mouse|Rat".

  2. How long will it take to receive "STK24 Antibody (OAAF04239)"?

    This item is available "Domestic: within 1-2 week delivery | International: 1-2 weeks".

  3. What buffer format is "STK24 Antibody (OAAF04239)" provided in?

    This item is provided in "Liquid".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "STK24 Antibody (OAAF04239)"?

    This target may also be called "epididymis secretory protein Li 95;HEL-S-95;mammalian STE20-like protein kinase 3;MST3;MST3B;serine/threonine kinase 24 (STE20 homolog, yeast);serine/threonine-protein kinase 24;STE20;STE20-like kinase 3;STE20-like kinase MST3;sterile 20-like kinase 3;STK3." in publications.

  5. What is the shipping cost for "STK24 Antibody (OAAF04239)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "STK24 Antibody (OAAF04239)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "STK24 Antibody (OAAF04239)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "49 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "STK24 Antibody (OAAF04239)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "STK24"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "STK24"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "STK24"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "STK24"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "STK24"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "STK24"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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