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Catalog No: ARP38256_P050
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ARP38256_P050
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Datasheets/ManualsPrintable datasheet for anti-STAT5A (ARP38256_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Pig, Rabbit, Sheep
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the C terminal region of human STAT5A
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 93%; Dog: 100%; Goat: 93%; Guinea Pig: 79%; Horse: 93%; Human: 100%; Mouse: 92%; Pig: 93%; Rabbit: 86%; Rat: 92%; Sheep: 93%
Peptide SequenceSynthetic peptide located within the following region: DQAPSPAVCPQAPYNMYPQNPDHVLDQDGEFDLDETMDVARHVEELLRRP
Concentration0.5 mg/ml
Blocking PeptideFor anti-STAT5A (ARP38256_P050) antibody is Catalog # AAP38256 (Previous Catalog # AAPP23110)
ReferenceKimura,M., (2008) Mol. Cell. Biol. 28 (11), 3830-3849
Gene SymbolSTAT5A
Gene Full NameSignal transducer and activator of transcription 5A
Alias SymbolsMGF, STAT5
NCBI Gene Id6776
Protein NameSignal transducer and activator of transcription 5A
Description of TargetSTAT5A is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Uniprot IDP42229
Protein Accession #NP_003143
Nucleotide Accession #NM_003152
Protein Size (# AA)794
Molecular Weight91kDa
Protein InteractionsTCF12; NLK; LEF1; NARF; CBL; UBC; ESR1; HELZ; UGT2B4; STAT5A; POM121C; WASH2P; AQP11; ZNF596; MRPS6; TXNDC11; RBMX; INSR; GLUD1; FN1; EPAS1; CYP2C9; CSNK2B; JAK2; BTK; EPOR; CRKL; SOCS7; NFKB1; ERBB4; EP300; MYB; SQSTM1; GNB2; SMARCA4; PGR; FGFR2; JAK3; C
  1. What is the species homology for "STAT5A Antibody - C-terminal region (ARP38256_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Pig, Rabbit, Sheep".

  2. How long will it take to receive "STAT5A Antibody - C-terminal region (ARP38256_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "STAT5A Antibody - C-terminal region (ARP38256_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "STAT5A Antibody - C-terminal region (ARP38256_P050)"?

    This target may also be called "MGF, STAT5" in publications.

  5. What is the shipping cost for "STAT5A Antibody - C-terminal region (ARP38256_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "STAT5A Antibody - C-terminal region (ARP38256_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "STAT5A Antibody - C-terminal region (ARP38256_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "91kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "STAT5A Antibody - C-terminal region (ARP38256_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "STAT5A"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "STAT5A"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "STAT5A"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "STAT5A"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "STAT5A"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "STAT5A"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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