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Catalog No: ARP40416_P050
Price: $0.00
SKU
ARP40416_P050
Availability: Domestic: within 1-2 days delivery | International: 1-2 days
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  • $55: Antibody & Protein in US
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Datasheets/ManualsPrintable datasheet for anti-SRGN (ARP40416_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Rat, Guinea Pig, Horse, Pig, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human SRGN
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceGuinea Pig: 78%; Horse: 100%; Human: 100%; Pig: 91%; Rabbit: 86%; Rat: 93%
Peptide SequenceSynthetic peptide located within the following region: RTDLFPKTRIQDLNRIFPLSEDYSGSGFGSGSGSGSGSGSGFLTEMEQDY
Concentration0.5 mg/ml
Blocking PeptideFor anti-SRGN (ARP40416_P050) antibody is Catalog # AAP40416 (Previous Catalog # AAPS02912)
ReferenceMa,D., (2008) Pediatr Blood Cancer 50 (5), 1067-1069
Gene SymbolSRGN
Gene Full NameSerglycin
Alias SymbolsPPG, PRG, PRG1
NCBI Gene Id5552
Protein NameSerglycin
Description of TargetSRGN is a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. SRGN was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis.This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Uniprot IDP10124
Protein Accession #NP_002718
Nucleotide Accession #NM_002727
Protein Size (# AA)158
Molecular Weight18kDa
Protein InteractionsUBQLN1; SGTA; UBQLN4; PSRC1; CEP70; UBR4; BAG6; CCL3; PF4; GZMB; CD44; ALB;
  1. What is the species homology for "SRGN Antibody - middle region (ARP40416_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Rat, Guinea Pig, Horse, Pig, Rabbit".

  2. How long will it take to receive "SRGN Antibody - middle region (ARP40416_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "SRGN Antibody - middle region (ARP40416_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "SRGN Antibody - middle region (ARP40416_P050)"?

    This target may also be called "PPG, PRG, PRG1" in publications.

  5. What is the shipping cost for "SRGN Antibody - middle region (ARP40416_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "SRGN Antibody - middle region (ARP40416_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "SRGN Antibody - middle region (ARP40416_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "18kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "SRGN Antibody - middle region (ARP40416_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "SRGN"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "SRGN"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "SRGN"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "SRGN"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "SRGN"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "SRGN"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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