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Datasheets/Manuals | Printable datasheet for SOX4 Antibody - N-terminal region (OABB02101) |
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Tested Species Reactivity | Human, Mouse |
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Predicted Species Reactivity | Hamster|Human|Mouse |
Product Format | Lyophilized. Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. |
Clonality | Polyclonal |
Clone | Polyclonal |
Isotype | Rabbit IgG |
Host | Rabbit |
Application | Western blot |
Additional Information | Notes: Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. |
:: | Background: Transcription factor SOX-4 is a protein that in humans is encoded by the SOX4 gene. This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). This protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. |
Reconstitution and Storage | 2°C to 8°C|-20°C |
Immunogen | Polypeptide |
Purification | Affinity Purified |
Peptide Sequence | Synthetic peptide located within the following region: MVQQTNNAENTEALLAGESSDSGAGLELGIA |
Concentration | 500 ug/ml |
Specificity | No cross reactivity with other proteins. |
Application Info | Western blot: 0.1-0.5 ug/ml: Human, Mouse |
Reference | 1. "Entrez Gene: SOX4 SRY (sex determining region Y)-box 4". 2. Critcher R, Stitson RN, Wade-Martins R, Easty DJ, Farr CJ (October 1998). "Assignment of Sox4 to mouse chromosome 13 bands A3-A5 by fluorescence in situ hybridization; refinement of the human SOX4 location to 6p22.3 and of SOX20 to chromosome 17p12.3". Cytogenet Cell Genet81 (3–4): 294–5. 3. Farr CJ, Easty DJ, Ragoussis J, Collignon J, Lovell-Badge R, Goodfellow PN (January 1994). "Characterization and mapping of the human SOX4 gene". Mamm Genome 4 (10): 577–84. |
Storage Buffer | Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. |
Description | Rabbit IgG polyclonal antibody for Transcription factor SOX-4(SOX4) detection. Tested with WB in Human;Mouse. |
Gene Symbol | SOX4 |
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Gene Full Name | SRY-box transcription factor 4 |
Alias Symbols | CSS10;ecotropic viral integration site 16;EVI16;SRY (sex determining region Y)-box 4;SRY-box 4;SRY-related HMG-box gene 4;transcription factor SOX-4. |
NCBI Gene Id | 6659 |
Protein Name | Transcription factor SOX-4 |
Description of Target | Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif. |
Uniprot ID | Q06945 |
Molecular Weight | 47263 MW |
- Protocol:
- Reconstitution & Storage Instructions
- Western Blotting/Immunoblotting (WB/IB) Protocol
- Immunohistochemistry (IHC) Protocol
- Immunocytochemistry (ICC) Protocol
- Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
- Blocking Peptide Competition Protocol (BPCP)
- Immunoprecipitation (IP) Protocol
- Antibody Array (AA) Protocol
- Tips Information:
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See our General FAQ page.
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What is the species homology for "SOX4 Antibody - N-terminal region (OABB02101)"?
The tested species reactivity for this item is "Human, Mouse". This antibody is predicted to have homology to "Hamster|Human|Mouse".
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How long will it take to receive "SOX4 Antibody - N-terminal region (OABB02101)"?
This item is available "Domestic: within 1-2 week delivery | International: within 1-2 week delivery".
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What buffer format is "SOX4 Antibody - N-terminal region (OABB02101)" provided in?
This item is provided in "Lyophilized. Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "SOX4 Antibody - N-terminal region (OABB02101)"?
This target may also be called "CSS10;ecotropic viral integration site 16;EVI16;SRY (sex determining region Y)-box 4;SRY-box 4;SRY-related HMG-box gene 4;transcription factor SOX-4." in publications.
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What is the shipping cost for "SOX4 Antibody - N-terminal region (OABB02101)"?
The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.
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What is the guarantee for "SOX4 Antibody - N-terminal region (OABB02101)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "SOX4 Antibody - N-terminal region (OABB02101)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "47263 MW".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "SOX4 Antibody - N-terminal region (OABB02101)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "SOX4"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "SOX4"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "SOX4"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "SOX4"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "SOX4"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "SOX4"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.