SLC39A4 Antibody - N-terminal region (ARP44090_P050)

Catalog No: ARP44090_P050

25 ug of the indicated Human whole cell extracts was loaded onto a 12% SDS-PAGE gel. 5 ug/mL of the antibody was used in this experiment.

Host: Rabbit
Target Name: SLC39A4
Sample Tissue: Human Ovary Tumor
Antibody Dilution: 1ug/ml

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Cow, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC39A4
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 86%; Human: 100%; Rabbit: 86%
• Peptide Sequence: Synthetic peptide located within the following region: ASLVSLELGLLLAVLVVTATASPPAGLLSLLTSGQGALDQEALGGLLNTL
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-SLC39A4 (ARP44090_P050) antibody is Catalog # AAP44090 (Previous Catalog # AAPP25536)
• Enhanced Validation:

  Relative Expression (Western Blot)

• Reference: Li,M., (2007) Proc. Natl. Acad. Sci. U.S.A. 104 (47), 18636-18641
• Publications:

  Computation and Functional Studies Provide a Model for the Structure of the Zinc Transporter hZIP4. J. Biol. Chem. 290, 17796-805 (2015). 25971965

Target Info

• Gene Symbol: SLC39A4
• Gene Full Name: Solute carrier family 39 (zinc transporter), member 4
• Alias Symbols: AEZ, ZIP4, AWMS2
• NCBI Gene Id: 55630
• Protein Name: Zinc transporter ZIP4
• Description of Target: SLC39A4 is a member of the zinc/iron-regulated transporter-like protein (ZIP) family. The transmembrane protein is required for zinc uptake in the intestine. Mutations in the gene encoding SLC39A4 result in acrodermatitis enteropathica, a rare inherited defect in the absorption of dietary zinc.This gene encodes a member of the zinc/iron-regulated transporter-like protein (ZIP) family. The transmembrane protein is required for zinc uptake in the intestine. Mutations in this gene result in acrodermatitis enteropathica, a rare inherited defect in the absorption of dietary zinc. Multiple transcript variants encoding different isoforms have been found for this gene.
• Uniprot ID: Q6P5W5
• Protein Accession #: NP_570901
• Nucleotide Accession #: NM_130849
• Protein Size (# AA): 647
• Molecular Weight: 68kDa
• Protein Interactions: UBC;