Catalog No: ARP44244_P050
Price: $0.00
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ARP44244_P050
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Datasheets/ManualsPrintable datasheet for anti-SGCB (ARP44244_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the middle region of human SGCB
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: FSTDYETHEFHLPSGVKSLNVQKASTERITSNATSDLNIKVDGRAIVRGN
Concentration0.5 mg/ml
Blocking PeptideFor anti-SGCB (ARP44244_P050) antibody is Catalog # AAP44244 (Previous Catalog # AAPP25624)
Enhanced Validation
WBY
SPR
YCHAROS
ReferenceDraviam,R.A., (2006) Muscle Nerve 34 (6), 691-701
Gene SymbolSGCB
Gene Full NameSarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
Alias SymbolsA3b, SGC, LGMD2E, LGMDR4
NCBI Gene Id6443
Protein NameBeta-sarcoglycan
Description of TargetSGCB is a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix.The dystrophin-glycoprotein complex (DGC) is a multisubunit protein complex that spans the sarcolemma and provides structural linkage between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. There are 3 main subcomplexes of the DGC: the cytoplasmic proteins dystrophin (DMD; MIM 300377) and syntrophin (SNTA1; MIM 601017), the alpha- and beta-dystroglycans (see MIM 128239), and the sarcoglycans (see, e.g., SGCA; MIM 600119) (Crosbie et al., 2000 [PubMed 10942431]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1235 BC020709.1 1-1235 1236-1833 U31116.1 1257-1854 1834-4229 AK094731.1 47-2442
Uniprot IDQ16585
Protein Accession #NP_000223
Nucleotide Accession #NM_000232
Protein Size (# AA)318
Molecular Weight35 kDa
Protein InteractionsUBC; SGCZ; SGCG; SGCD; SGCA;
  1. What is the species homology for "SGCB Antibody - middle region (ARP44244_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit".

  2. How long will it take to receive "SGCB Antibody - middle region (ARP44244_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "SGCB Antibody - middle region (ARP44244_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "SGCB Antibody - middle region (ARP44244_P050)"?

    This target may also be called "A3b, SGC, LGMD2E, LGMDR4" in publications.

  5. What is the shipping cost for "SGCB Antibody - middle region (ARP44244_P050)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "SGCB Antibody - middle region (ARP44244_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "SGCB Antibody - middle region (ARP44244_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "35 kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "SGCB Antibody - middle region (ARP44244_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "SGCB"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "SGCB"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "SGCB"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "SGCB"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "SGCB"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "SGCB"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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