SERPIND1 Antibody (OAAF02111)

Catalog No: OAAF02111 (Formerly GWB-ASD373)

Size:100 ug

Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue, using Heparin Cofactor II Antibody. The picture on the right is treated with the synthesized peptide.

Immunofluorescence analysis of HepG2 cells, using Heparin Cofactor II Antibody. The picture on the right is treated with the synthesized peptide.

Product Info

• Predicted Species Reactivity: Human|Mouse|Rat
• Product Format: Liquid
• Clonality: Polyclonal
• Host: Rabbit
• Application: Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
• Reconstitution and Storage: -20°C
• Immunogen: The antiserum was produced against synthesized peptide derived from human Heparin Cofactor II.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Specificity: Heparin Cofactor II antibody detects endogenous levels of total Heparin Cofactor II protein.
• Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Dilution: The optimal working dilution should be determined by the end user.
• Application Info: IHC: 1:50~1:100; IF: 1:100~1:500; ELISA: 1:5000
• Reference: Blinder M.A., Biochemistry 27:752-759(1988).
  Herzog R., Biochemistry 30:1350-1357(1991).
  Collins J.E., Genome Biol. 5:RESEARCH84.1-RESEARCH84.11(2004).

Target Info

• Gene Symbol: SERPIND1
• Gene Full Name: serpin family D member 1
• Alias Symbols: D22S673;HC2;HCF2;HCII;heparin cofactor 2;Heparin cofactor II;heparin cofactor II splice isoform;HLS2;leuserpin 2;LS2;protease inhibitor leuserpin-2;serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1;serpin D1;serpin peptidase inhibitor, clade D (heparin cofactor), member 1;THPH10.
• NCBI Gene Id: 3053
• Protein Name: Heparin cofactor 2
• Description of Target: Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner.
• Uniprot ID: P05546
• Protein Accession #: NP_000176.2
• Molecular Weight: 57 kDa