SECISBP2 Antibody - N-terminal region (ARP41002_P050)

Catalog No: ARP41002_P050

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WB Suggested Anti-SECISBP2 Antibody
Titration: 1.0 ug/ml
Positive Control: PANC1 Whole Cell

Product Info

• Tested Species Reactivity: Human
• Predicted Species Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
• Product Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Clonality: Polyclonal
• Host: Rabbit
• Application: WB
• Reconstitution and Storage: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
• Purification: Affinity Purified
• Predicted Homology Based on Immunogen Sequence: Cow: 76%; Dog: 86%; Guinea Pig: 91%; Horse: 83%; Human: 100%; Mouse: 92%; Rabbit: 86%; Rat: 92%
• Peptide Sequence: Synthetic peptide located within the following region: FDSERADGTISSEIKSARGSHHLSIYAENSLKSDGYHKRTDRKSRIIAKN
• Concentration: 0.5 mg/ml
• Blocking Peptide: For anti-SECISBP2 (ARP41002_P050) antibody is Catalog # AAP41002

Target Info

• Gene Symbol: SECISBP2
• Gene Full Name: SECIS binding protein 2
• Alias Symbols: SBP2
• NCBI Gene Id: 79048
• Protein Name: Selenocysteine insertion sequence-binding protein 2
• Description of Target: The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism.
• Uniprot ID: Q96T21
• Protein Accession #: NP_076982
• Nucleotide Accession #: NM_024077
• Protein Size (# AA): 854
• Molecular Weight: 95kDa
• Protein Interactions: GOLGA2; SMAD9; APP; ATXN7L3;